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Ken-Ichi Nihei

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Articles 66
Citations 443
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Recent Articles
1.
Alberto-Silva C, Portaro F, Kodama R, Gomes L, Silva B, da Cunha E Silva F, et al.
Toxins (Basel) . 2024 Oct; 16(10). PMID: 39453222
A comprehensive LC-MS study examined the venom components of the solitary scoliid wasp . Online mass fingerprinting showed that crude venom contains 25 small molecules (amino acids, biogenic amines, and...
2.
Sato Y, Weng Y, Shimazaki T, Yoshida K, Nihei K, Okamoto M
Biochem Biophys Res Commun . 2024 Sep; 734:150624. PMID: 39226738
Wheat (Triticum aestivum) is a major staple crop worldwide, and its yields are significantly threatened by wheat powdery mildew (Blumeria graminis f. sp. tritici). Enhancing disease resistance in wheat is...
3.
Alberto-Silva C, Portaro F, Kodama R, Pantaleao H, Inagaki H, Nihei K, et al.
Toxins (Basel) . 2021 Dec; 13(12). PMID: 34941722
Venoms of solitary wasps are utilized for prey capture (insects and spiders), paralyzing them with a stinger injection to be offered as food for their larvae. Thus, the identification and...
4.
Alberto-Silva C, Portaro F, Kodama R, Pantaleao H, Rangel M, Nihei K, et al.
J Venom Anim Toxins Incl Trop Dis . 2021 Jul; 27:e20200171. PMID: 34194483
Background: Solitary wasp venoms may be a rich source of neuroactive substances, since their venoms are used for paralyzing preys. We have been exploring bioactive constituents of solitary wasp venoms...
5.
Nihei K, Peigneur S, Tytgat J, Lange A, Konno K
Peptides . 2021 May; 142:170575. PMID: 34023397
Purification of small peptide components in the venoms of the solitary sphecid wasps, Sphex argentatus argentatus and Isodontia harmandi, led to the isolation of several major peptides. Analysis of MS/MS...
6.
Shimakage R, Nihei K
Nat Prod Res . 2020 Sep; 36(7):1803-1811. PMID: 32924592
Phloretin-4--β-D-glucopyranoside (), isolated from , was synthesized for the first time through aldol condensation and Schmidt glycosylation reactions aiming to develop a novel hydrophilic tyrosinase inhibitor. However, the specific rotation...
7.
Radis-Baptista G, Dodou H, Prieto-da-Silva A, Zaharenko A, Kazuma K, Nihei K, et al.
Biol Chem . 2020 Apr; 401(8):945-954. PMID: 32229648
Ants (Hymenoptera, Apocrita, Aculeata, Formicoidea) comprise a well-succeeded group of animals. Like bees and wasps, ants are mostly venomous, having a sting system to deliver a mixture of bioactive organic...
8.
Nihei K, Kubo I
Appl Biochem Biotechnol . 2020 Mar; 191(4):1711-1716. PMID: 32212107
The oxidation of 4-t-butylcatechol catalyzed by mushroom tyrosinase was inhibited by 4-bromobenzaldehyde, 4-chlorobenzaldehyde, 4-fluorobenzaldehyde, 4-cyanobenzaldehyde, and 4-nitrobenzaldehyde with 50% inhibitory concentrations of 114 μM, 175 μM, 387 μM, 822 μM,...
9.
Radis-Baptista G, Dodou H, Prieto-da-Silva A, Zaharenko A, Kazuma K, Nihei K, et al.
Biol Chem . 2020 Feb; PMID: 32087061
Ants (Hymenoptera, Apocrita, Aculeata, Formicoidea) comprise a well-succeeded group of animals. Like bees and wasps, ants are mostly venomous, having a sting system to deliver a mixture of bioactive organic...
10.
Nihei K, Kubo I
Int J Biol Macromol . 2019 Apr; 133:929-932. PMID: 31026526
As a novel mushroom tyrosinase inhibitor, 4-methoxybenzonitrile (anisnitrile) was identified (IC = 111.1 μM) with hyperbolic inhibition manner. The calculated αK (166.3 μM) was larger than K (66.5 μM) by...