Keith E Mostov
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Explore the profile of Keith E Mostov including associated specialties, affiliations and a list of published articles.
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71
Citations
4707
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Recent Articles
1.
Nedvetsky P, Cornelissen I, Mathivet T, Bouleti C, Ou P, Baatsen P, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232721
During vascular development, endothelial cAMP-dependent protein kinase A (PKA) regulates angiogenesis by controlling the number of tip cells, and PKA inhibition leads to excessive angiogenesis. Whether this role of endothelial...
2.
Yang Y, Paivinen P, Xie C, Krup A, Makela T, Mostov K, et al.
Nat Commun
. 2021 Dec;
12(1):7186.
PMID: 34893605
How tubular organs elongate is poorly understood. We found that attenuated ciliary Hedgehog signaling in the gut wall impaired patterning of the circumferential smooth muscle and inhibited proliferation and elongation...
3.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al.
Nat Rev Mol Cell Biol
. 2021 Oct;
22(12):834.
PMID: 34654908
No abstract available.
4.
Pandita A, Ekstrand M, Bjursten S, Zhao Z, Fogelstrand P, Le Gal K, et al.
Am J Pathol
. 2021 Aug;
191(11):2023-2038.
PMID: 34400131
Angiogenesis supplies oxygen and nutrients to growing tumors. Inhibiting angiogenesis may stop tumor growth, but vascular endothelial growth factor inhibitors have limited effect in most tumors. This limited effect may...
5.
Wang T, Kwon S, Peng X, Urdy S, Lu Z, Schmitz R, et al.
iScience
. 2020 Oct;
23(10):101629.
PMID: 33089114
Madin-Darby canine kidney II (MDCKII) cells are widely used to study epithelial morphogenesis. To better understand this process, we performed time course RNA-seq analysis of MDCKII 3D cystogenesis, along with...
6.
Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, et al.
Nat Rev Mol Cell Biol
. 2020 Apr;
21(6):341-352.
PMID: 32300252
Epithelial-mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occurs in a diverse range...
7.
Yu W, Marshall W, Metzger R, Brakeman P, Morsut L, Lim W, et al.
Cell Syst
. 2019 Sep;
9(3):221-227.
PMID: 31557453
Many metazoan organs are comprised of branching trees of epithelial tubes; how patterning occurs in these trees is a fundamental problem of development. Commonly, branch tips fill the volume of...
8.
Roman-Fernandez A, Roignot J, Sandilands E, Nacke M, Mansour M, McGarry L, et al.
Nat Commun
. 2018 Nov;
9(1):5041.
PMID: 30487552
Apical-basal polarization is essential for epithelial tissue formation, segregating cortical domains to perform distinct physiological functions. Cortical lipid asymmetry has emerged as a determinant of cell polarization. We report a...
9.
Kwon S, Oh S, Nacke M, Mostov K, Lipschutz J
J Biol Chem
. 2017 Oct;
292(40):16523.
PMID: 28986432
No abstract available.
10.
Datta A, Sandilands E, Mostov K, Bryant D
Cell Signal
. 2017 Sep;
40:91-98.
PMID: 28888686
The formation of lumens in epithelial tissues requires apical-basal polarization of cells, and the co-ordination of this individual polarity collectively around a contiguous lumen. Signals from the Extracellular Matrix (ECM)...