David M Bryant
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Explore the profile of David M Bryant including associated specialties, affiliations and a list of published articles.
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49
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2372
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Recent Articles
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Neilson L, Cartwright D, Risteli M, Jokinen E, McGarry L, Sandvik T, et al.
Matrix Biol Plus
. 2024 Jan;
19-20:100136.
PMID: 38223308
High-grade serous (HGS) ovarian cancer is the most lethal gynaecological disease in the world and metastases is a major cause. The omentum is the preferential metastatic site in HGS ovarian...
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Nikolatou K, Bryant D, Sandilands E
Biochem Soc Trans
. 2023 Aug;
51(4):1559-1569.
PMID: 37622523
The ability to remodel and move cellular membranes, and the cargoes regulated by these membranes, allows for specialised functions to occur in distinct regions of the cell in a process...
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Nikolatou K, Sandilands E, Roman-Fernandez A, Cumming E, Freckmann E, Lilla S, et al.
EMBO J
. 2023 Aug;
42(18):e113987.
PMID: 37577760
Dysregulation of the PI3K/AKT pathway is a common occurrence in high-grade serous ovarian carcinoma (HGSOC), with the loss of the tumour suppressor PTEN in HGSOC being associated with poor prognosis....
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Sandilands E, Freckmann E, Cumming E, Roman-Fernandez A, McGarry L, Anand J, et al.
J Cell Biol
. 2023 Mar;
222(4).
PMID: 36880595
ARF GTPases are central regulators of membrane trafficking that control local membrane identity and remodeling facilitating vesicle formation. Unraveling their function is complicated by the overlapping association of ARFs with...
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Roman-Fernandez A, Mansour M, Kugeratski F, Anand J, Sandilands E, Galbraith L, et al.
Sci Adv
. 2023 Feb;
9(5):eabq1858.
PMID: 36735782
The glycocalyx component and sialomucin podocalyxin (PODXL) is required for normal tissue development by promoting apical membranes to form between cells, triggering lumen formation. Elevated PODXL expression is also associated...
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Freckmann E, Sandilands E, Cumming E, Neilson M, Roman-Fernandez A, Nikolatou K, et al.
Nat Commun
. 2022 Sep;
13(1):5317.
PMID: 36085324
Single cell profiling by genetic, proteomic and imaging methods has expanded the ability to identify programmes regulating distinct cell states. The 3-dimensional (3D) culture of cells or tissue fragments provides...
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Kai F, Ou G, Tourdot R, Stashko C, Gaietta G, Swift M, et al.
EMBO J
. 2022 Jul;
41(17):e109205.
PMID: 35880301
Patient-derived organoids and cellular spheroids recapitulate tissue physiology with remarkable fidelity. We investigated how engagement with a reconstituted basement membrane in three dimensions (3D) supports the polarized, stress resilient tissue...
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Bristow R, Engel J, Jayasinghe I, Kampmann M, James Sansom O, Bryant D
J Cell Sci
. 2022 Feb;
135(4).
PMID: 35188214
February is LGBT+ history month, and to celebrate, Journal of Cell Science Editorial Advisory Board member David Bryant organised a conversation with a selection of scientists to explore their experiences...