Kazunori Ikebukuro
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Explore the profile of Kazunori Ikebukuro including associated specialties, affiliations and a list of published articles.
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157
Citations
1176
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Recent Articles
1.
Moriya M, Oyama T, Goto M, Ikebukuro K, Yoshida W
STAR Protoc
. 2025 Feb;
6(1):103646.
PMID: 39985771
G-quadruplex and intercalated motif are quadruplex structures of which sequences are enriched in promoters. Here, we present a protocol for circular dichroism spectral analysis of the thermal stability of CpG-methylated...
2.
Pathak S, Le N, Oyama T, Odahara Y, Momotake A, Ikebukuro K, et al.
Biomolecules
. 2025 Jan;
15(1).
PMID: 39858489
Synthetic cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) are promising candidates for vaccine adjuvants, because they activate immune responses through the Toll-like receptor 9 (TLR9) pathway. However, unmodified CpG ODNs are quickly degraded...
3.
Yamada T, Furusho A, Kojima K, Sugiyama E, Mizuno H, Tsukakoshi K, et al.
Biosens Bioelectron
. 2025 Jan;
272():117108.
PMID: 39764977
We developed a novel DNA aptamer, D8#24S1, which specifically recognizes mertansine (DM1), the cytotoxic payload of the antibody-drug conjugate (ADC) trastuzumab emtansine (T-DM1), and applied it for T-DM1 analysis. D8#24S1...
4.
Miura D, Hayashi W, Hirano K, Sasaki I, Tsukakoshi K, Kakizoe H, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(43):e2403871.
PMID: 39316377
The SARS-CoV-2 pandemic has challenged more scientists to detect viruses and to visualize virus-containing spots for diagnosis and infection control; however, detection principles of commercially available technologies are not optimal...
5.
Hoshi K, Tu A, Shobo M, Kettisen K, Ye L, Bulow L, et al.
Nanomaterials (Basel)
. 2024 Sep;
14(17).
PMID: 39269102
Hemozoin (Hz) is a heme crystal produced during malaria infection that stimulates immune cells, leading to the production of cytokines and chemokines. The immunostimulatory action of Hz has previously been...
6.
Oda M, Hiraka K, Tsugawa W, Ikebukuro K, Sode K, Asano R
Biosens Bioelectron
. 2024 Sep;
267:116741.
PMID: 39250870
Antibody-enzyme complexes (AECs) are ideal for immunosensing. Although AECs using antibody fragments can be produced by bacterial hosts, their low affinity limits their sensing applications. We have improved the affinity...
7.
Hamasaki M, Takamatsu S, Nagata M, Wilson E, Suzuki H, Tanaka A, et al.
Biosens Bioelectron
. 2024 Jun;
261:116511.
PMID: 38917513
Single-chain fragment variables (scFvs), composed of variable heavy and light chains joined together by a peptide linker, can be produced using a cost-effective bacterial expression system, making them promising candidates...
8.
Yamada T, Tsukakoshi K, Furusho A, Sugiyama E, Mizuno H, Hayashi H, et al.
Talanta
. 2024 Jun;
277:126349.
PMID: 38852342
We developed an aptamer-based fluorescence resonance energy transfer (FRET) assay capable of recognizing therapeutic monoclonal antibody bevacizumab and rapidly quantifying its concentration with just one mixing step. In this assay,...
9.
Ikegai K, Okuda-Shimazaki J, Tran T, Hatada M, Asano R, Ikebukuro K, et al.
Biosens Bioelectron
. 2024 Mar;
255:116219.
PMID: 38552525
We introduce a versatile method to convert NAD or NADP -dependent dehydrogenases into quasi-direct electron transfer (quasi-DET)-type dehydrogenases, by modifying with a mediator on the enzyme surface toward the development...
10.
Miura D, Motohashi S, Goto A, Kimura H, Tsugawa W, Sode K, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474105
Although IgG-free immunosensors are in high demand owing to ethical concerns, the development of convenient immunosensors that alternatively integrate recombinantly produced antibody fragments, such as single-chain variable fragments (scFvs), remains...