Kaori Tsukakoshi
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Explore the profile of Kaori Tsukakoshi including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
242
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Recent Articles
1.
Yamada T, Furusho A, Kojima K, Sugiyama E, Mizuno H, Tsukakoshi K, et al.
Biosens Bioelectron
. 2025 Jan;
272():117108.
PMID: 39764977
We developed a novel DNA aptamer, D8#24S1, which specifically recognizes mertansine (DM1), the cytotoxic payload of the antibody-drug conjugate (ADC) trastuzumab emtansine (T-DM1), and applied it for T-DM1 analysis. D8#24S1...
2.
Miura D, Hayashi W, Hirano K, Sasaki I, Tsukakoshi K, Kakizoe H, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(43):e2403871.
PMID: 39316377
The SARS-CoV-2 pandemic has challenged more scientists to detect viruses and to visualize virus-containing spots for diagnosis and infection control; however, detection principles of commercially available technologies are not optimal...
3.
Yamada T, Tsukakoshi K, Furusho A, Sugiyama E, Mizuno H, Hayashi H, et al.
Talanta
. 2024 Jun;
277:126349.
PMID: 38852342
We developed an aptamer-based fluorescence resonance energy transfer (FRET) assay capable of recognizing therapeutic monoclonal antibody bevacizumab and rapidly quantifying its concentration with just one mixing step. In this assay,...
4.
Kaku T, Ikebukuro K, Tsukakoshi K
J Biochem
. 2024 Mar;
175(6):575-585.
PMID: 38430131
Amyloidosis is characterized by the abnormal accumulation of amyloid proteins. The causative proteins aggregate from monomers to oligomers and fibrils, among which some intermediate oligomers are considered as major toxins....
5.
Komiya E, Takamatsu S, Miura D, Tsukakoshi K, Tsugawa W, Sode K, et al.
J Am Chem Soc
. 2024 Jan;
146(6):4087-4097.
PMID: 38295327
DNA-protein complexes are attractive components with broad applications in various research fields, such as DNA aptamer-enzyme complexes as biosensing elements. However, noncovalent DNA-protein complexes often decrease detection sensitivity because they...
6.
Numaguchi Y, Tsukakoshi K, Takeuchi N, Suzuki Y, Ikebukuro K, Kawano R
PNAS Nexus
. 2023 Dec;
3(1):pgad437.
PMID: 38156289
This study describes the observation of the transformation of monomeric amyloid β (Aβ42) into oligomers in a lipid membrane utilizing a lipid bilayer system for electrophysiological measurement. The relevance of...
7.
Rokutani S, Hiraka K, Saitoh H, Saito T, Nonaka Y, Ueno K, et al.
Biosens Bioelectron
. 2023 Nov;
245:115827.
PMID: 37979546
A simple and sensitive homogeneous protein detection system is required for the early detection of biomarkers. Thermo-responsive magnetic particles (TM) have already been developed to achieve easy bound/free separation at...
8.
Todoroki K, Hamada D, Yamada T, Saito T, Shimizu Y, Sugiyama E, et al.
Anal Sci
. 2023 Sep;
39(11):1805-1811.
PMID: 37660341
We report on the development of a versatile and accurate bioanalytical method for bevacizumab using a pretreatment method combining affinity purification with anti-idiotypic DNA aptamers and centrifugal ultrafiltration concentration, followed...
9.
Murakami T, Kaku T, Tsukakoshi K, Iwaide S, Itoh Y, Hisada M, et al.
Vet Pathol
. 2023 Jan;
60(2):203-213.
PMID: 36680468
Mammary tumor-associated amyloidosis (MTAA) in dogs is characterized by amyloid deposition in the stroma of mammary adenoma or carcinoma; however, the amyloid precursor protein remains unknown. We attempted to identify...
10.
Tsukakoshi K, Kubo R, Ikebukuro K
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36498917
Amyloid β (Aβ) oligomers play a key role in the progression of Alzheimer's disease (AD). Multiple forms of Aβ assemblies have been identified by in vitro and in vivo analyses;...