Isao Karube
Overview
Explore the profile of Isao Karube including associated specialties, affiliations and a list of published articles.
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Articles
53
Citations
225
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Recent Articles
1.
Yoshida W, Terasaka M, Laddachote S, Karube I
Biochim Biophys Acta Gen Subj
. 2018 Jun;
1862(9):1933-1937.
PMID: 29940278
Background: DNA methylation at the 5-position of cytosine is an epigenetic modification of CpG dinucleotides. In addition to CpG methylation, the G-quadruplex (G4) structure has been reported as a regulator...
2.
Yoshida W, Saikyo H, Nakabayashi K, Yoshioka H, Bay D, Iida K, et al.
Sci Rep
. 2018 Feb;
8(1):3116.
PMID: 29449667
G-quadruplex (G4) is a DNA secondary structure that has been found to play regulatory roles in the genome. The identification of G4-forming sequences is important to study the specific structure-function...
3.
Yoshida W, Baba Y, Banzawa K, Karube I
Anal Chim Acta
. 2017 Oct;
990:168-173.
PMID: 29029740
Global DNA methylation levels have been considered as biomarkers for cancer diagnostics because transposable elements that constitute approximately 45% of the human genome are hypomethylated in cancer cells. We have...
4.
Bay D, Busch A, Lisdat F, Iida K, Ikebukuro K, Nagasawa K, et al.
BMC Mol Biol
. 2017 Jun;
18(1):17.
PMID: 28655335
Background: G-quadruplex is a DNA secondary structure that has been shown to play an important role in biological systems. In a previous study, we identified 1998 G-quadruplex-forming sequences using a...
5.
Yoshida W, Baba Y, Karube I
Anal Chem
. 2016 Aug;
88(18):9264-8.
PMID: 27541340
DNA methylation plays an important role in the regulation of gene expression. In normal cells, transposable elements that constitute approximately 45% of the human genome are highly methylated to silence...
6.
Yoshida W, Yoshioka H, Bay D, Iida K, Ikebukuro K, Nagasawa K, et al.
Anal Chem
. 2016 Jun;
88(14):7101-7.
PMID: 27351368
DNA methylation has been proposed as one of the promising biomarkers for cancer diagnosis. In this study, we developed a DNA methylation detection system utilizing G-quadruplex and i-motif-forming sequences that...
7.
Clark D, Karube I, Sode K, Bulow L, Bruggemann O, Lowe C, et al.
Biotechnol Bioeng
. 2015 Jan;
112(4):645-7.
PMID: 25599981
No abstract available.
8.
Prieto-Simon B, Karube I, Saiki H
Food Chem
. 2012 Sep;
135(3):1323-9.
PMID: 22953861
Ochratoxin A (OTA) is a mycotoxin found in a wide range of food and feedstuffs. Intake of OTA-contaminated food causes health concern due to the harmful effects reported on humans...
9.
Hashimoto Y, Nakamura H, Asaga K, Karube I
Microbes Environ
. 2011 May;
23(1):35-9.
PMID: 21558685
We have developed a new system for the rapid diagnosis of soil-borne diseases, consisting of two biosensors. The system was constructed using equal quantities of two different microbes, each individually...
10.
Inaba Y, Koide S, Yokoyama K, Karube I
J Chromatogr Sci
. 2011 Mar;
49(4):303-9.
PMID: 21439122
A novel separation method of urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) was developed. The C(18) and the strong cation-exchange (SCX) columns were employed to separate urinary 8-OHdG. The major interfering substances were removed...