Kazuo Nagasawa
Overview
Explore the profile of Kazuo Nagasawa including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
164
Citations
1304
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Fujita K, Hayashi M, Yoshihara M, Nomura S, Kitami K, Miyamoto E, et al.
Med Mol Morphol
. 2025 Feb;
PMID: 39964447
Ovarian cancer (OvCa) is a leading cause of gynecological cancer-related mortality, primarily due to peritoneal dissemination, which facilitates metastasis in the abdominal cavity. This study explored the potential of vitamin...
2.
Iwaki M, Sakamoto R, Tsutsumi R, Sawada T, Hirokawa T, Kato S, et al.
Chembiochem
. 2025 Jan;
:e202401038.
PMID: 39843389
Vitamin D receptor (VDR) plays a critical role in regulating multiple biological processes, including bone metabolism and cell differentiation, by mediating transcriptional activation in response to ligand binding. We have...
3.
Takemoto M, Delghandi S, Abo M, Yurimoto K, Odagi M, Singh V, et al.
J Am Chem Soc
. 2025 Jan;
147(3):2902-2912.
PMID: 39794153
Despite the unprecedented therapeutic potential of immune checkpoint antibody therapies, their efficacy is limited partly by the dysfunction of T cells within the cancer microenvironment. Combination therapies with small molecules...
4.
Ishikawa R, Yanagita K, Shimada S, Sasaki S, Hirokawa T, Ma Y, et al.
Chem Commun (Camb)
. 2024 Oct;
60(92):13550-13553.
PMID: 39474792
The novel photo-crosslinking ligand 6OTD-Bp, bearing an alkylamine benzophenone (Bp) with macrocyclic hexaoxazole (6OTD), was shown to preferentially ligate with hybrid G4s through recognizing both G-quartets and their characteristic wide...
5.
Iijima K, Sakamoto R, Tsutsumi R, Nakaya N, Hirokawa T, Odagi M, et al.
Chem Pharm Bull (Tokyo)
. 2024 Oct;
72(10):899-908.
PMID: 39428509
25-Hydroxyvitamin D-23,26-lactone (1) and 1α,25-dihydroxyvitamin D-23,26-lactone (2) have long been considered as among the end metabolites of vitamin D. Recently, however, we found that these lactones exhibit biological activity related...
6.
Hirozumi R, Hakamada M, Minowa T, Cho Y, Kudo Y, Konoki K, et al.
Chem Asian J
. 2024 Sep;
19(24):e202400834.
PMID: 39305001
The synthesis and biosynthesis of the complex saxitoxin (STX) structure have garnered significant interest. Previously, we hypothesized that the tricyclic skeleton of STX originates from the monocyclic precursor 11-hydroxy-IntC'2 during...
7.
Hakamada M, Tokairin C, Ishizuka H, Adachi K, Osawa T, Aonuma S, et al.
Chemistry
. 2024 Jan;
30(18):e202304238.
PMID: 38270276
Saxitoxin (STX, 1) is a representative compound of paralytic shellfish toxins (PSTs) that are produced by marine dinoflagellates and freshwater cyanobacteria. Although several pathways have been proposed for the biosynthesis...
8.
Iwaki M, Kanemoto Y, Sawada T, Nojiri K, Kurokawa T, Tsutsumi R, et al.
PLoS One
. 2023 Dec;
18(12):e0295288.
PMID: 38091304
Vitamin D (VD) exerts a wide variety of biological functions including calcemic activity. VD nutritional status is closely associated with the onset and development of chronic diseases. To develop a...
9.
Kanemoto Y, Iwaki M, Sawada T, Nojiri K, Kurokawa T, Tsutsumi R, et al.
J Bone Metab
. 2023 Sep;
30(3):219-229.
PMID: 37718900
Vitamin D (VD) exerts a wide variety of biological actions in addition to its well-known roles in calcium homeostasis. Nutritional VD deficiency induces rachitic abnormalities in growing children and osteomalacia...
10.
Mizumoto Y, Sakamoto R, Iijima K, Nakaya N, Odagi M, Tera M, et al.
Biomolecules
. 2023 Jul;
13(7).
PMID: 37509072
Vitamin D () is metabolized by various cytochrome P450 (CYP) enzymes, resulting in the formation of diverse metabolites. Among them, 4α,25-dihydroxyvitamin D () and 4β,25-dihydroxyvitamin D () are both produced...