Kasey Jividen
Overview
Explore the profile of Kasey Jividen including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
481
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0
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Recent Articles
1.
Yang C, Jividen K, Kamata T, Dworak N, Oostdyk L, Remlein B, et al.
Nat Commun
. 2021 May;
12(1):2705.
PMID: 33976187
Androgen signaling through the androgen receptor (AR) directs gene expression in both normal and prostate cancer cells. Androgen regulates multiple aspects of the AR life cycle, including its localization and...
2.
Costa-Pinheiro P, Heher A, Raymond M, Jividen K, Shaw J, Paschal B, et al.
iScience
. 2020 Dec;
23(12):101855.
PMID: 33313495
Anti-androgens are a common therapy in prostate cancer (PCa) targeting androgen receptor (AR) signaling. However, these therapies fail due to selection of highly aggressive AR-negative cancer cells that have no...
3.
Lazzarotto C, Malinin N, Li Y, Zhang R, Yang Y, Lee G, et al.
Nat Biotechnol
. 2020 Jun;
38(11):1317-1327.
PMID: 32541958
Current methods can illuminate the genome-wide activity of CRISPR-Cas9 nucleases, but are not easily scalable to the throughput needed to fully understand the principles that govern Cas9 specificity. Here we...
4.
Kamata T, Yang C, Jividen K, Spencer A, Dworak N, Oostdyk L, et al.
Methods Mol Biol
. 2019 May;
1966:107-124.
PMID: 31041742
ADP-ribosylation is a posttranslational modification generated by members of the superfamily of ADP-ribosyltransferases, known as the Parp enzymes. Depending on the superfamily member, Parp enzymes can mono- or poly-ADP-ribosylate a...
5.
Dworak N, Makosa D, Chatterjee M, Jividen K, Yang C, Snow C, et al.
Aging Cell
. 2018 Dec;
18(1):e12851.
PMID: 30565836
The Ran GTPase regulates nuclear import and export by controlling the assembly state of transport complexes. This involves the direct action of RanGTP, which is generated in the nucleus by...
6.
Oostdyk L, Shank L, Jividen K, Dworak N, Sherman N, Paschal B
Methods
. 2018 Nov;
157:66-79.
PMID: 30419333
The discovery and validation of protein-protein interactions provides a knowledge base that is critical for defining protein networks and how they underpin the biology of the cell. Identification of protein...
7.
Jividen K, Kedzierska K, Yang C, Szlachta K, Ratan A, Paschal B
BMC Cancer
. 2018 Oct;
18(1):960.
PMID: 30305041
Background: The cellular effects of androgen are transduced through the androgen receptor, which controls the expression of genes that regulate biosynthetic processes, cell growth, and metabolism. Androgen signaling also impacts...
8.
Yang C, Melhuish T, Spencer A, Ni L, Hao Y, Jividen K, et al.
Prostate
. 2017 Sep;
77(15):1452-1467.
PMID: 28875501
Background: Phosphoinositide-3 (PI-3) kinase signaling has a pervasive role in cancer. One of the key effectors of PI-3 kinase signaling is AKT, a kinase that promotes growth and survival in...
9.
Yang C, Jividen K, Spencer A, Dworak N, Ni L, Oostdyk L, et al.
Mol Cell
. 2017 May;
66(4):503-516.e5.
PMID: 28525742
ADP-ribosylation of proteins is emerging as an important regulatory mechanism. Depending on the family member, ADP-ribosyltransferases either conjugate a single ADP-ribose to a target or generate ADP-ribose chains. Here we...
10.
Jividen K, Li H
Genes Chromosomes Cancer
. 2014 Aug;
53(12):963-71.
PMID: 25131334
A hallmark of many neoplasias is chromosomal rearrangement, an event that commonly results in the fusion of two separate genes. The RNA and protein resulting from these gene fusions often...