Karl Willert
Overview
Explore the profile of Karl Willert including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
3876
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lopes A, Paulino A, Thaumaturgo M, Araujo W, Caloba P, Kawanishi K, et al.
Cancer Lett
. 2025 Mar;
616:217598.
PMID: 40023392
Colorectal cancer (CRC) is a significant health concern, often linked to western diets, particularly red meat consumption. Several mechanisms, such as the high heme iron content, the formation of N-nitroso...
2.
Yamaguchi T, Willert K
Curr Top Dev Biol
. 2023 Mar;
153:xv-xvi.
PMID: 36967204
No abstract available.
3.
Sonavane P, Willert K
Curr Top Dev Biol
. 2023 Mar;
153:95-119.
PMID: 36967203
The role of Wnt signaling in stem cells has been mired in seemingly contradictory findings. On one hand, Wnt has been heralded as a self-renewal factor. On the other hand,...
4.
Trieger G, Pessentheiner A, Purcell S, Green C, DeForest N, Willert K, et al.
J Biol Chem
. 2023 Mar;
299(5):104611.
PMID: 36931394
Adipose tissue plays a crucial role in maintaining metabolic homeostasis by storing lipids and glucose from circulation as intracellular fat. As peripheral tissues like adipose tissue become insulin resistant, decompensation...
5.
Sonavane P, Willert K
Methods Mol Biol
. 2022 Feb;
2438:123-131.
PMID: 35147939
Wnt proteins are secreted, lipid-modified growth factors with a wide range of activities across all metazoan species. Their production, secretion, and signaling range are under tight cellular control such that...
6.
Do M, Wu C, Sonavane P, Juarez E, Adams S, Ross J, et al.
Mol Cancer Ther
. 2021 Oct;
21(1):113-124.
PMID: 34667113
Although WNT signaling is frequently dysregulated in solid tumors, drugging this pathway has been challenging due to off-tumor effects. Current clinical pan-WNT inhibitors are nonspecific and lead to adverse effects,...
7.
Chai G, Szenker-Ravi E, Chung C, Li Z, Wang L, Khatoo M, et al.
N Engl J Med
. 2021 Sep;
385(14):1292-1301.
PMID: 34587386
Background: Structural birth defects occur in approximately 3% of live births; most such defects lack defined genetic or environmental causes. Despite advances in surgical approaches, pharmacologic prevention remains largely out...
8.
Sonavane P, Willert K
Handb Exp Pharmacol
. 2021 Aug;
269:3-28.
PMID: 34463853
Wnt signaling is critical for proper development of the embryo and for tissue homeostasis in the adult. Activation of this signaling cascade is initiated by binding of the secreted Wnts...
9.
Gumber D, Do M, Suresh Kumar N, Sonavane P, Wu C, Cruz L, et al.
Elife
. 2020 Dec;
9.
PMID: 33331818
WNT proteins are secreted symmetry breaking signals that interact with cell surface receptors of the FZD family to regulate a multitude of developmental processes. Studying selectivity between WNTs and FZDs...
10.
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon C, et al.
Nat Cell Biol
. 2019 May;
21(6):721-730.
PMID: 31110287
Wnt signalling drives many processes in development, homeostasis and disease; however, the role and mechanism of individual ligand-receptor (Wnt-Frizzled (Fzd)) interactions in specific biological processes remain poorly understood. Wnt9a is...