Kacey J Prentice
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Explore the profile of Kacey J Prentice including associated specialties, affiliations and a list of published articles.
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24
Citations
605
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Recent Articles
1.
Podobnik J, Prentice K
Diabetes Obes Metab
. 2025 Jan;
27(3):1032-1044.
PMID: 39757938
Type 1 diabetes (T1D) is classically characterized as an autoimmune disease wherein the immune system erroneously attacks insulin-producing pancreatic β-cells, causing insulin insufficiency and severe metabolic dysregulation. However, intensive investigation...
2.
Izadifar M, Massumi M, Prentice K, Oussenko T, Li B, Elbaz J, et al.
Stem Cell Res Ther
. 2024 Dec;
15(1):486.
PMID: 39696686
Background: Pluripotent cell-derived islet replacement therapy offers promise for treating Type 1 diabetes (T1D), but concerns about uncontrolled cell proliferation and tumorigenicity present significant safety challenges. To address the safety...
3.
Piro A, Luo Y, Zhang Z, Ye W, Kang F, Xie L, et al.
Mol Cell Endocrinol
. 2024 Sep;
594:112376.
PMID: 39321953
Zinc transporter 8 (ZnT8) is highly expressed in pancreatic beta cells, localizes to insulin secretory granules (ISG), and regulates zinc content. ZnT8 gene polymorphisms have revealed a relationship between ZnT8...
4.
Inouye K, Prentice K, Lee A, Wang Z, Dominguez-Gonzalez C, Chen M, et al.
JCI Insight
. 2023 Jun;
8(14).
PMID: 37279064
Fatty acid binding protein 4 (FABP4) is a lipid chaperone secreted from adipocytes upon stimulation of lipolysis. Circulating FABP4 levels strongly correlate with obesity and metabolic pathologies in experimental models...
5.
Prentice K, Lee A, Cedillo P, Inouye K, Ertunc M, Riveros J, et al.
J Lipid Res
. 2023 May;
64(6):100386.
PMID: 37172691
Levels of circulating fatty acid binding protein 4 (FABP4) protein are strongly associated with obesity and metabolic disease in both mice and humans, and secretion is stimulated by β-adrenergic stimulation...
6.
Prentice K, Saksi J, Robertson L, Lee G, Inouye K, Eguchi K, et al.
Nature
. 2021 Dec;
600(7890):720-726.
PMID: 34880500
The liberation of energy stores from adipocytes is critical to support survival in times of energy deficit; however, uncontrolled or chronic lipolysis associated with insulin resistance and/or insulin insufficiency disrupts...
7.
Giroud M, Jodeleit H, Prentice K, Bartelt A
J Physiol
. 2021 Sep;
600(5):1189-1208.
PMID: 34555180
Obesity is a medical disorder caused by multiple mechanisms of dysregulated energy balance. A major consequence of obesity is an increased risk to develop diabetes, diabetic complications and cardiovascular disease....
8.
Glavas M, Hui Q, Miao I, Yang F, Erener S, Prentice K, et al.
Sci Rep
. 2021 Jul;
11(1):14032.
PMID: 34234216
Overconsumption of saturated fats promotes obesity and type 2 diabetes. Excess weight gain in early life may be particularly detrimental by promoting earlier diabetes onset and potentially by adversely affecting...
9.
Prentice K, Saksi J, Hotamisligil G
J Lipid Res
. 2019 Feb;
60(4):734-740.
PMID: 30705117
Although counterregulatory hormones and mediators of the fight-or-flight responses are well defined at many levels, how energy stores per se are integrated into this system remains an enigmatic question. Recent...
10.
Mohan H, Brandt S, Kim J, Wong F, Lai M, Prentice K, et al.
Diabetes Obes Metab
. 2018 Aug;
21(1):61-72.
PMID: 30062833
Aim: Omega-3 fatty acid ethyl ester supplements, available by prescription, are common in the treatment of dyslipidaemia in humans. Recent studies show that 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a metabolite formed from...