Justin B Steinfeld
Overview
Explore the profile of Justin B Steinfeld including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
7
Citations
365
Followers
0
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Recent Articles
1.
Steinfeld J, Belan O, Kwon Y, Terakawa T, Al-Zain A, Smith M, et al.
Genes Dev
. 2024 May;
38(7-8):354.
PMID: 38772725
No abstract available.
2.
Xue C, Molnarova L, Steinfeld J, Zhao W, Ma C, Spirek M, et al.
Nucleic Acids Res
. 2020 Dec;
49(1):285-305.
PMID: 33332547
RECQ5 is one of five RecQ helicases found in humans and is thought to participate in homologous DNA recombination by acting as a negative regulator of the recombinase protein RAD51....
3.
Steinfeld J, Belan O, Kwon Y, Terakawa T, Al-Zain A, Smith M, et al.
Genes Dev
. 2019 Aug;
33(17-18):1191-1207.
PMID: 31371435
The vast majority of eukaryotes possess two DNA recombinases: Rad51, which is ubiquitously expressed, and Dmc1, which is meiosis-specific. The evolutionary origins of this two-recombinase system remain poorly understood. Interestingly,...
4.
Zhao W, Steinfeld J, Liang F, Chen X, Maranon D, Ma C, et al.
Nature
. 2017 Oct;
550(7676):360-365.
PMID: 28976962
The tumour suppressor complex BRCA1-BARD1 functions in the repair of DNA double-stranded breaks by homologous recombination. During this process, BRCA1-BARD1 facilitates the nucleolytic resection of DNA ends to generate a...
5.
Lee J, Steinfeld J, Qi Z, Kwon Y, Sung P, Greene E
J Biol Chem
. 2017 May;
292(26):11125-11135.
PMID: 28476890
Homologous recombination plays key roles in double-strand break repair, rescue, and repair of stalled replication forks and meiosis. The broadly conserved Rad51/RecA family of recombinases catalyzes the DNA strand invasion...
6.
Lee J, Terakawa T, Qi Z, Steinfeld J, Redding S, Kwon Y, et al.
Science
. 2015 Aug;
349(6251):977-81.
PMID: 26315438
DNA strand exchange plays a central role in genetic recombination across all kingdoms of life, but the physical basis for these reactions remains poorly defined. Using single-molecule imaging, we found...
7.
Steinfeld J, Aerni H, Rogulina S, Liu Y, Rinehart J
ACS Chem Biol
. 2014 Mar;
9(5):1104-12.
PMID: 24646179
Adding nonstandard amino acids to the genetic code of E. coli expands the chemical and biological functional space for proteins. This is accomplished with engineered, orthogonal aminoacyl-tRNA synthetase and tRNA...