» Authors » Jurate Bitinaite

Jurate Bitinaite

Explore the profile of Jurate Bitinaite including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 18
Citations 737
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Vaiskunaite R, Vainauskas J, Morris J, Potapov V, Bitinaite J
Nucleic Acids Res . 2022 Apr; 50(8):4616-4629. PMID: 35420131
Prokaryotic Argonautes (pAgos) use small nucleic acids as specificity guides to cleave single-stranded DNA at complementary sequences. DNA targeting function of pAgos creates attractive opportunities for DNA manipulations that require...
2.
Shah S, Sanchez J, Stewart A, Piperakis M, Cosstick R, Nichols C, et al.
PLoS One . 2015 Apr; 10(4):e0124783. PMID: 25880668
SgrAI is a type II restriction endonuclease with an unusual mechanism of activation involving run-on oligomerization. The run-on oligomer is formed from complexes of SgrAI bound to DNA containing its...
3.
Pais J, Dai N, Tamanaha E, Vaisvila R, Fomenkov A, Bitinaite J, et al.
Proc Natl Acad Sci U S A . 2015 Apr; 112(14):4316-21. PMID: 25831492
Modified DNA bases in mammalian genomes, such as 5-methylcytosine ((5m)C) and its oxidized forms, are implicated in important epigenetic regulation processes. In human or mouse, successive enzymatic conversion of (5m)C...
4.
Dai N, Bitinaite J, Chin H, Pradhan S, Correa Jr I
Chembiochem . 2013 Oct; 14(16):2144-52. PMID: 24106095
5-(hydroxymethyl)cytosine (5-hmC) is a newly identified oxidative product of 5-methylcytosine (5-mC) in the mammalian genome, and is believed to be an important epigenetic marker influencing a variety of biological processes....
5.
Vaisvila R, Bitinaite J
Methods Mol Biol . 2013 Feb; 978:165-71. PMID: 23423896
Gene synthesis is an invaluable technique in synthetic and molecular biology for synthesis of artificial genes, operons, and even genomes. In many cases the traditional methods for obtaining functional DNA...
6.
Terragni J, Bitinaite J, Zheng Y, Pradhan S
Biochemistry . 2012 Jan; 51(5):1009-19. PMID: 22229759
5-Hydroxymethylcytosine (5-hmC) is an enzymatic oxidative product of 5-methylcytosine (5-mC). The Ten Eleven Translocation (TET) family of enzymes catalyze the conversion of 5-mC to 5-hmC. Phage-encoded glucosyltransferases are known to...
7.
Morey Kinney S, Chin H, Vaisvila R, Bitinaite J, Zheng Y, Esteve P, et al.
J Biol Chem . 2011 May; 286(28):24685-93. PMID: 21610077
Cytosine residues in the vertebrate genome are enzymatically modified to 5-methylcytosine, which participates in transcriptional repression of genes during development and disease progression. 5-Methylcytosine can be further enzymatically modified to...
8.
Little E, Dunten P, Bitinaite J, Horton N
Acta Crystallogr D Biol Crystallogr . 2011 Jan; 67(Pt 1):67-74. PMID: 21206063
SgrAI is a type II restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-activation with expansion of DNA-sequence specificity. The three-dimensional crystal structures of SgrAI bound...
9.
Park C, Joshi H, Agrawal A, Ghare M, Little E, Dunten P, et al.
PLoS Biol . 2010 Dec; 8(12):e1000554. PMID: 21151881
SgrAI is a type IIF restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of cleavage activity and sequence specificity. Previous studies have shown that DNA...
10.
Park C, Stiteler A, Shah S, Ghare M, Bitinaite J, Horton N
Biochemistry . 2010 Sep; 49(41):8818-30. PMID: 20836535
SgrAI is a type II restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of DNA activity and sequence specificity. Precleaved primary site DNA has been...