Richard J Roberts
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Explore the profile of Richard J Roberts including associated specialties, affiliations and a list of published articles.
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180
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4535
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Recent Articles
1.
Johnson S, Weigele P, Fomenkov A, Ge A, Vincze A, Eaglesham J, et al.
Nucleic Acids Res
. 2024 Dec;
53(2.
PMID: 39657740
The availability of large databases of biological sequences presents an opportunity for in-depth exploration of gene diversity and function. Bacterial defense systems are a rich source of diverse but difficult...
2.
Soto-Serrano A, Li W, Panah F, Hui Y, Atienza P, Fomenkov A, et al.
Microb Genom
. 2024 Nov;
10(11).
PMID: 39526732
The reconstruction of complete bacterial genomes is essential for microbial research, offering insights into genetic content, ontology and regulation. While Pacific Biosciences (PacBio) provides high-quality genomes, its cost remains a...
3.
Soto L, DasSarma P, Anton B, Vincze T, Verma I, Eralp B, et al.
Microbiol Resour Announc
. 2024 Oct;
13(11):e0077824.
PMID: 39431873
sp. strain NMX12-1, an extremely halophilic Archaeon, was isolated from 250 million-year-old Salado Formation salt crystal in Carlsbad, New Mexico. Single-molecule real-time sequencing revealed a 3.2-Mbp genome with a 2.6-Mbp...
4.
Valentin-Alvarado L, Shi L, Appler K, Crits-Christoph A, De Anda V, Adler B, et al.
Genome Res
. 2024 Oct;
34(10):1595-1609.
PMID: 39406503
Asgard archaea are of great interest as the progenitors of Eukaryotes, but little is known about the mobile genetic elements (MGEs) that may shape their ongoing evolution. Here, we describe...
5.
Vale F, Roberts R, Kobayashi I, Camargo M, Rabkin C
Gut Microbes
. 2024 Aug;
16(1):2379440.
PMID: 39132840
Prophages can have major clinical implications through their ability to change pathogenic bacterial traits. There is limited understanding of the prophage role in ecological, evolutionary, adaptive processes and pathogenicity of...
6.
Yang W, Luyten Y, Reister E, Mangelson H, Sisson Z, Auch B, et al.
bioRxiv
. 2024 Jul;
PMID: 39071437
Methylation patterns in bacteria can be used to study Restriction-Modification (RM) or other defense systems with novel properties. While C and A methylation is well characterized mainly through PacBio sequencing,...
7.
Roberts R, Lam C
Biomolecules
. 2024 Jul;
14(7).
PMID: 39062578
Calcium regulation is essential in virtually any cell due to its critical role as a second messenger in multiple signaling pathways [...].
8.
Wu H, Fujisawa Y, Tozuka Z, Fomenkov A, Nakura Y, Kajiyama S, et al.
Enzyme Microb Technol
. 2024 Jul;
180:110471.
PMID: 38959818
Here, we report a novel endonuclease and N-adenine DNA methyltransferase (mA methyltransferase) in the Ureaplasma parvum SV3F4 strain. Our previous study found that the SV3F4 strain carries 17 unique genes,...
9.
Savijoki K, Deptula P, Roberts R, Hammaren M, Yli-Kauhaluoma J, Varmanen P, et al.
Microbiol Resour Announc
. 2024 Feb;
13(4):e0101623.
PMID: 38415640
, a slow-growing Actinobacterium, typically induces tuberculosis-like disease in fish. Here, we report a new reference sequence for ATCC 927, along with its DNA methylome. This aims to maximize the...
10.
Aparicio-Blanco J, Vishwakarma N, Lehr C, Prestidge C, Thomas N, Roberts R, et al.
Drug Deliv Transl Res
. 2024 Feb;
14(6):1725-1734.
PMID: 38341386
Antimicrobial resistance and tolerance (AMR&T) are urgent global health concerns, with alarmingly increasing numbers of antimicrobial drugs failing and a corresponding rise in related deaths. Several reasons for this situation...