Pete W Dunten
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Explore the profile of Pete W Dunten including associated specialties, affiliations and a list of published articles.
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11
Citations
167
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Recent Articles
1.
Fyfe A, Dunten P, Martick M, Scott W
J Mol Biol
. 2015 Apr;
427(12):2205-19.
PMID: 25861762
Guanine-rich sequences can, under appropriate conditions, adopt a distinctive, four-stranded, helical fold known as a G-quadruplex. Interest in quadruplex folds has grown in recent years as evidence of their biological...
2.
Smith C, Card G, Cohen A, Doukov T, Eriksson T, Gonzalez A, et al.
J Appl Crystallogr
. 2011 Dec;
43(Pt 5):1261-1270.
PMID: 22184477
For the past five years, the Structural Molecular Biology group at the Stanford Synchrotron Radiation Lightsource (SSRL) has provided general users of the facility with fully remote access to the...
3.
Dharmarajan L, Kraszewski J, Mukhopadhyay B, Dunten P
Proteins
. 2011 Apr;
79(6):1820-9.
PMID: 21491491
The crystal structure of an archaeal-type phosphoenolpyruvate carboxylase from Clostridium perfringens has been determined based on X-ray data extending to 3 Å. The asymmetric unit of the structure includes two...
4.
Little E, Dunten P, Bitinaite J, Horton N
Acta Crystallogr D Biol Crystallogr
. 2011 Jan;
67(Pt 1):67-74.
PMID: 21206063
SgrAI is a type II restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-activation with expansion of DNA-sequence specificity. The three-dimensional crystal structures of SgrAI bound...
5.
Park C, Joshi H, Agrawal A, Ghare M, Little E, Dunten P, et al.
PLoS Biol
. 2010 Dec;
8(12):e1000554.
PMID: 21151881
SgrAI is a type IIF restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of cleavage activity and sequence specificity. Previous studies have shown that DNA...
6.
Kertesz D, Brotherton-Pleiss C, Yang M, Wang Z, Lin X, Qiu Z, et al.
Bioorg Med Chem Lett
. 2010 Jun;
20(14):4215-8.
PMID: 20538456
An analysis of the binding motifs of known HIV-1 non-nucleoside reverse transcriptase inhibitors has led to discovery of novel piperidine-linked aminopyrimidine derivatives with broad activity against wild-type as well as...
7.
Martin F, Baskaran P, Ma X, Dunten P, Schaefer M, Stasch J, et al.
J Biol Chem
. 2010 May;
285(29):22651-7.
PMID: 20463019
Heme is a vital molecule for all life forms with heme being capable of assisting in catalysis, binding ligands, and undergoing redox changes. Heme-related dysfunction can lead to cardiovascular diseases...
8.
Dharmarajan L, Kraszewski J, Mukhopadhyay B, Dunten P
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2009 Nov;
65(Pt 11):1193-6.
PMID: 19923749
An archaeal-type phosphoenolpyruvate carboxylase (PepcA) from Clostridium perfringens has been expressed in Escherichia coli in a soluble form with an amino-terminal His tag. The recombinant protein is enzymatically active and...
9.
Dunten P, Little E, Horton N
Acta Crystallogr D Biol Crystallogr
. 2009 Mar;
65(Pt 4):393-8.
PMID: 19307723
Uninterpretable electron-density maps were obtained using either MIRAS phases or MR phases in attempts to determine the structure of the type II restriction endonuclease SgrAI bound to DNA. While neither...
10.
Dunten P, Little E, Gregory M, Manohar V, Dalton M, Hough D, et al.
Nucleic Acids Res
. 2008 Aug;
36(16):5405-16.
PMID: 18701646
The three-dimensional X-ray crystal structure of the 'rare cutting' type II restriction endonuclease SgrAI bound to cognate DNA is presented. SgrAI forms a dimer bound to one duplex of DNA....