Jooho Chung
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Explore the profile of Jooho Chung including associated specialties, affiliations and a list of published articles.
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19
Citations
617
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Recent Articles
1.
Chung J, Kim J, Blazier J, Hwangbo M, Chu K
Microbiol Resour Announc
. 2023 Sep;
12(10):e0033123.
PMID: 37728590
We report the draft genome of LAC1 isolated from an acidic aquifer in Indian Head, MD, USA. The genome contains 5,883,000 bp and has a GC content of 70% with...
2.
Maniaci B, Chung J, Sanz-Altamira P, DeAngelo D, Maxson J
Haematologica
. 2022 Dec;
108(7):1945-1950.
PMID: 36579444
No abstract available.
3.
Jin X, Ng V, Zhao M, Liu L, Higashimoto T, Lee Z, et al.
Dis Model Mech
. 2022 Mar;
15(5).
PMID: 35352806
RAS mutations occur in a broad spectrum of human hematopoietic malignancies. Activating Ras mutations in blood cells leads to hematopoietic malignancies in mice. In murine hematopoietic stem cells (HSCs), mutant...
4.
Perkey E, De Sousa D, Carrington L, Chung J, Dils A, Granadier D, et al.
J Immunol
. 2020 Feb;
204(6):1674-1688.
PMID: 32060138
Notch signaling is emerging as a critical regulator of T cell activation and function. However, there is no reliable cell surface indicator of Notch signaling across activated T cell subsets....
5.
Chung J, Radojcic V, Perkey E, Parnell T, Niknafs Y, Jin X, et al.
J Immunol
. 2019 Jun;
203(2):557-568.
PMID: 31182480
Graft-versus-host disease (GVHD) is the most serious complication of allogeneic hematopoietic cell transplantation. Notch signals delivered during the first 48 h after transplantation drive proinflammatory cytokine production in conventional T...
6.
Radojcic V, Paz K, Chung J, Du J, Perkey E, Flynn R, et al.
Blood
. 2018 Sep;
132(20):2188-2200.
PMID: 30181175
Chronic graft-versus-host disease (cGVHD) is a major complication of allogeneic hematopoietic cell transplantation (allo-HCT) and remains an area of unmet clinical need with few treatment options available. Notch blockade prevents...
7.
Srinivasan S, Cesa L, Li X, Julien O, Zhuang M, Shao H, et al.
Mol Cancer Res
. 2017 Oct;
16(1):58-68.
PMID: 28970360
Hsp70 is a molecular chaperone that binds to "client" proteins and protects them from protein degradation. Hsp70 is essential for the survival of many cancer cells, but it is not...
8.
Kimball A, Joshi A, Boniakowski A, Schaller M, Chung J, Allen R, et al.
Front Immunol
. 2017 Jun;
8:635.
PMID: 28620387
Macrophages are essential immune cells necessary for regulated inflammation during wound healing. Recent studies have identified that Notch plays a role in macrophage-mediated inflammation. Thus, we investigated the role of...
9.
Neal L, Qiu Y, Chung J, Xing E, Cho W, Malachowski A, et al.
J Immunol
. 2017 Jun;
199(2):643-655.
PMID: 28615417
is a ubiquitous, opportunistic fungal pathogen but the cell signaling pathways that drive T cell responses regulating antifungal immunity are incompletely understood. Notch is a key signaling pathway regulating T...
10.
Chung J, Ebens C, Perkey E, Radojcic V, Koch U, Scarpellino L, et al.
J Clin Invest
. 2017 Mar;
127(4):1574-1588.
PMID: 28319044
Alloimmune T cell responses induce graft-versus-host disease (GVHD), a serious complication of allogeneic bone marrow transplantation (allo-BMT). Although Notch signaling mediated by Delta-like 1/4 (DLL1/4) Notch ligands has emerged as...