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John W Hickey

Explore the profile of John W Hickey including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 1072
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Recent Articles
1.
Borner K, Blood P, Silverstein J, Ruffalo M, Satija R, Teichmann S, et al.
Nat Methods . 2025 Mar; PMID: 40082611
The Human BioMolecular Atlas Program (HuBMAP) aims to construct a 3D Human Reference Atlas (HRA) of the healthy adult body. Experts from 20+ consortia collaborate to develop a Common Coordinate...
2.
Zhu Y, Yao Z, Li S, Ma J, Wei C, Yu D, et al.
bioRxiv . 2025 Feb; PMID: 39975373
Hydrogel materials have emerged as versatile platforms for various biomedical applications. Notably, the engineered nanofiber-hydrogel composite (NHC) has proven effective in mimicking the soft tissue extracellular matrix, facilitating substantial recruitment...
3.
Drainas A, McIlwain D, Dallas A, Chu T, Delgado-Gonzalez A, Baron M, et al.
Nat Biomed Eng . 2025 Feb; PMID: 39939547
In serology, each sample is typically tested individually, one antigen at a time. This is costly and time consuming. Serology techniques should ideally allow recurrent measurements in parallel in small...
4.
Li S, Yao Z, Wang H, Ecker J, Omotoso M, Lee J, et al.
Sci Adv . 2024 Dec; 10(50):eadm7928. PMID: 39671478
Tissue-resident memory T (T) cells preferentially reside in peripheral tissues, serving as key players in tumor immunity and immunotherapy. The lack of effective approaches for expanding T cells and delivering...
5.
Aihara G, Clifton K, Chen M, Li Z, Atta L, Miller B, et al.
Bioinformatics . 2024 Jun; 40(7). PMID: 38902953
Motivation: Spatial omics data demand computational analysis but many analysis tools have computational resource requirements that increase with the number of cells analyzed. This presents scalability challenges as researchers use...
6.
Borner K, Blood P, Silverstein J, Ruffalo M, Satija R, Teichmann S, et al.
bioRxiv . 2024 Jun; PMID: 38826261
The Human BioMolecular Atlas Program (HuBMAP) aims to construct a reference 3D structural, cellular, and molecular atlas of the healthy adult human body. The HuBMAP Data Portal (https://portal.hubmapconsortium.org) serves experimental...
7.
Hickey J, Agmon E, Horowitz N, Tan T, Lamore M, Sunwoo J, et al.
Cell Syst . 2024 Apr; 15(4):322-338.e5. PMID: 38636457
Cancer progression is a complex process involving interactions that unfold across molecular, cellular, and tissue scales. These multiscale interactions have been difficult to measure and to simulate. Here, we integrated...
8.
Matusiak M, Hickey J, van IJzendoorn D, Lu G, Kidzinski L, Zhu S, et al.
Cancer Discov . 2024 Mar; 14(8):1418-1439. PMID: 38552005
Tumor-associated macrophages are transcriptionally heterogeneous, but the spatial distribution and cell interactions that shape macrophage tissue roles remain poorly characterized. Here, we spatially resolve five distinct human macrophage populations in...
9.
Jain S, Pei L, Spraggins J, Angelo M, Carson J, Gehlenborg N, et al.
Nat Cell Biol . 2024 Mar; 26(5):839. PMID: 38429479
No abstract available.
10.
Livingston N, Hickey J, Sim H, Salathe S, Choy J, Kong J, et al.
Adv Mater . 2024 Feb; 36(23):e2310043. PMID: 38358310
T cells are critical mediators of antigen-specific immune responses and are common targets for immunotherapy. Biomaterial scaffolds have previously been used to stimulate antigen-presenting cells to elicit antigen-specific immune responses;...