Jonathan P Schneck
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Explore the profile of Jonathan P Schneck including associated specialties, affiliations and a list of published articles.
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3030
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Recent Articles
1.
Ariail E, Biggs B, OFlanagan R, Schneck J
Immunol Invest
. 2025 Feb;
:1-19.
PMID: 39981682
Background: IL-7 is a cytokine that plays a critical role in the development and proliferation of many different immune cells. IL-7 is notably important for the proper development and activity...
2.
Zhu Y, Yao Z, Li S, Ma J, Wei C, Yu D, et al.
bioRxiv
. 2025 Feb;
PMID: 39975373
Hydrogel materials have emerged as versatile platforms for various biomedical applications. Notably, the engineered nanofiber-hydrogel composite (NHC) has proven effective in mimicking the soft tissue extracellular matrix, facilitating substantial recruitment...
3.
Li S, Yao Z, Wang H, Ecker J, Omotoso M, Lee J, et al.
Sci Adv
. 2024 Dec;
10(50):eadm7928.
PMID: 39671478
Tissue-resident memory T (T) cells preferentially reside in peripheral tissues, serving as key players in tumor immunity and immunotherapy. The lack of effective approaches for expanding T cells and delivering...
4.
Omotoso M, Est-Witte S, Shannon S, Li S, Nair N, Neshat S, et al.
Biomaterials
. 2024 Sep;
313:122773.
PMID: 39217794
The development of artificial Antigen Presenting Cells (aAPCs) has led to improvements in adoptive T cell therapy (ACT), an immunotherapy, for cancer treatment. aAPCs help to streamline the consistent production...
5.
Omotoso M, Lanis M, Schneck J
Curr Protoc
. 2024 Feb;
4(2):e976.
PMID: 38400601
Antigen-presenting cells (APCs), such as dendritic cells and macrophages, have a unique ability to survey the body and present information to T cells via peptide-loaded major histocompatibility complexes (signal 1)....
6.
Livingston N, Hickey J, Sim H, Salathe S, Choy J, Kong J, et al.
Adv Mater
. 2024 Feb;
36(23):e2310043.
PMID: 38358310
T cells are critical mediators of antigen-specific immune responses and are common targets for immunotherapy. Biomaterial scaffolds have previously been used to stimulate antigen-presenting cells to elicit antigen-specific immune responses;...
7.
Zhu Y, Ma J, Shen R, Lin J, Li S, Lu X, et al.
Nat Biomed Eng
. 2023 Dec;
8(5):544-560.
PMID: 38082180
Lipid nanoparticles (LNPs) can be designed to potentiate cancer immunotherapy by promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells and modulating the activity of adjuvants. Here...
8.
Ben-Akiva E, Hickey J, Meyer R, Isser A, Shannon S, Livingston N, et al.
Acta Biomater
. 2023 Feb;
160:187-197.
PMID: 36812956
Artificial antigen presenting cells are biomimetic particles that recapitulate the signals presented by natural antigen presenting cells in order to stimulate T cells in an antigen-specific manner using an acellular...
9.
Isser A, Silver A, Pruitt H, Mass M, Elias E, Aihara G, et al.
Nat Commun
. 2022 Oct;
13(1):6086.
PMID: 36241639
Helper (CD4) T cells perform direct therapeutic functions and augment responses of cells such as cytotoxic (CD8) T cells against a wide variety of diseases and pathogens. Nevertheless, inefficient synthetic...
10.
Chaisawangwong W, Wang H, Kouo T, Salathe S, Isser A, Bieler J, et al.
JCI Insight
. 2022 Sep;
7(18).
PMID: 36134660
Cross-reactive immunity between SARS-CoV-2 and other related coronaviruses has been well-documented, and it may play a role in preventing severe COVID-19. Epidemiological studies early in the pandemic showed a geographical...