Joel W Blanchard
Overview
Explore the profile of Joel W Blanchard including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
506
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0
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Recent Articles
1.
Mesentier-Louro L, Goldman C, Ndayisaba A, Buonfiglioli A, Rooklin R, Schuldt B, et al.
bioRxiv
. 2025 Feb;
PMID: 39975381
The pathological hallmark of neurodegenerative disease is the aberrant post-translational modification and aggregation of proteins leading to the formation of insoluble protein inclusions. Genetic factors like are known to increase...
2.
Blanchard J, Akay L, Davila-Velderrain J, von Maydell D, Mathys H, Davidson S, et al.
Nature
. 2024 Dec;
636(8043):E9.
PMID: 39633058
No abstract available.
3.
Goldman C, Kareva T, Sarrafha L, Schuldt B, Sahasrabudhe A, Ahfeldt T, et al.
bioRxiv
. 2024 Jul;
PMID: 38979135
Cellular processes including lysosomal and mitochondrial dysfunction are implicated in the development of many diseases. Quantitative visualization of mitochondria and lysosoesl is crucial to understand how these organelles are dysregulated...
4.
Li H, Przybyla L, Blanchard J
Front Cell Dev Biol
. 2024 Jan;
11:1351676.
PMID: 38188018
No abstract available.
5.
Goldman C, Suhy N, Schwarz J, Sartori E, Rooklin R, Schuldt B, et al.
J Vis Exp
. 2023 Nov;
(200).
PMID: 37929987
The blood-brain barrier (BBB) is a key physiological component of the central nervous system (CNS), maintaining nutrients, clearing waste, and protecting the brain from pathogens. The inherent barrier properties of...
6.
Stanton A, Bubnys A, Agbas E, James B, Shin Park D, Jiang A, et al.
bioRxiv
. 2023 Aug;
PMID: 37645757
Patient-specific, human-based cellular models integrating a biomimetic blood-brain barrier (BBB), immune, and myelinated neuron components are critically needed to enable accelerated, translationally relevant discovery of neurological disease mechanisms and interventions....
7.
Mesentier-Louro L, Suhy N, Broekaart D, Bula M, Pereira A, Blanchard J
Methods Mol Biol
. 2023 Jun;
2683:135-151.
PMID: 37300772
The blood-brain barrier (BBB) is a key physiological component of the brain, protecting the brain from peripheral processes and pathogens. The BBB is a dynamic structure that is heavily involved...
8.
Blanchard J, Akay L, Davila-Velderrain J, von Maydell D, Mathys H, Davidson S, et al.
Nature
. 2022 Nov;
611(7937):769-779.
PMID: 36385529
APOE4 is the strongest genetic risk factor for Alzheimer's disease. However, the effects of APOE4 on the human brain are not fully understood, limiting opportunities to develop targeted therapeutics for...
9.
Blanchard J, Victor M, Tsai L
Nat Rev Neurol
. 2021 Nov;
18(1):25-39.
PMID: 34750588
Alzheimer disease (AD) is the most prevalent type of dementia. It is marked by severe memory loss and cognitive decline, and currently has limited effective treatment options. Although individuals with...
10.
Blanchard J, Bula M, Davila-Velderrain J, Akay L, Zhu L, Frank A, et al.
Nat Med
. 2021 Jan;
27(2):356.
PMID: 33514950
No abstract available.