Joan W Conaway
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Explore the profile of Joan W Conaway including associated specialties, affiliations and a list of published articles.
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4431
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Recent Articles
21.
Wu D, Zhao L, Feng Z, Yu C, Ding J, Wang L, et al.
J Biol Chem
. 2017 Apr;
292(24):10014-10025.
PMID: 28450392
The human males absent on the first (MOF)-containing histone acetyltransferase nonspecific lethal (NSL) complex comprises nine subunits including the -linked -acetylglucosamine (-GlcNAc) transferase, isoform 1 (OGT1). However, whether the -GlcNAc...
22.
Weems J, Slaughter B, Unruh J, Boeing S, Hall S, McLaird M, et al.
J Biol Chem
. 2017 Mar;
292(16):6431-6437.
PMID: 28292928
Elongin A performs dual functions as the transcriptionally active subunit of RNA polymerase II (Pol II) elongation factor Elongin and as the substrate recognition subunit of a Cullin-RING E3 ubiquitin...
23.
Tsai K, Yu X, Gopalan S, Chao T, Zhang Y, Florens L, et al.
Nature
. 2017 Feb;
544(7649):196-201.
PMID: 28241144
The conserved Mediator co-activator complex has an essential role in the regulation of RNA polymerase II transcription in all eukaryotes. Understanding the structure and interactions of Mediator is crucial for...
24.
Sato S, Tomomori-Sato C, Tsai K, Yu X, Sardiu M, Saraf A, et al.
J Biol Chem
. 2016 Nov;
291(52):26886-26898.
PMID: 27821593
Mediator plays an integral role in activation of RNA polymerase II (Pol II) transcription. A key step in activation is binding of Mediator to Pol II to form the Mediator-Pol...
25.
Boeing S, Williamson L, Encheva V, Gori I, Saunders R, Instrell R, et al.
Cell Rep
. 2016 May;
15(7):1597-1610.
PMID: 27184836
In order to facilitate the identification of factors and pathways in the cellular response to UV-induced DNA damage, several descriptive proteomic screens and a functional genomics screen were performed in...
26.
Masuda Y, Takahashi H, Sato S, Tomomori-Sato C, Saraf A, Washburn M, et al.
Nat Commun
. 2015 Jun;
6:7299.
PMID: 26095369
Although DNA double-strand break (DSB) repair is mediated by numerous proteins accumulated at DSB sites, how DNA repair proteins are assembled into damaged chromatin has not been fully elucidated. Here...
27.
Weems J, Slaughter B, Unruh J, Hall S, McLaird M, Gilmore J, et al.
J Biol Chem
. 2015 Apr;
290(24):15030-41.
PMID: 25878247
Elongin A performs dual functions in cells as a component of RNA polymerase II (Pol II) transcription elongation factor Elongin and as the substrate recognition subunit of a Cullin-RING E3...
28.
Conaway R, Conaway J
Nat Rev Mol Cell Biol
. 2015 Feb;
16(3):128.
PMID: 25693123
No abstract available.
29.
Takahashi H, Takigawa I, Watanabe M, Anwar D, Shibata M, Tomomori-Sato C, et al.
Nat Commun
. 2015 Jan;
6:5941.
PMID: 25575120
Regulation of transcription elongation by RNA polymerase II (Pol II) is a key regulatory step in gene transcription. Recently, the little elongation complex (LEC)-which contains the transcription elongation factor ELL/EAF-was...
30.
Wang L, Limbo O, Fei J, Chen L, Kim B, Luo J, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
111(52):18566-71.
PMID: 25512493
CSB/ERCC6 (Cockayne syndrome B protein/excision repair cross-complementation group 6), a member of a subfamily of SWI2/SNF2 (SWItch/sucrose nonfermentable)-related chromatin remodelers, plays crucial roles in gene expression and the maintenance of...