Orchestrating Transcription with the Pol II CTD

Overview

Journal Nat Rev Mol Cell Biol

Specialties Cell Biology
Molecular Biology

Date 2015 Feb 19

PMID 25693123

Citations 3

Authors

Ronald C Conaway

Joan W Conaway

Affiliations

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Citing Articles

CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation.

Qiu M, Yin Z, Wang H, Lei L, Li C, Cui Y Sci Adv. 2023; 9(20):eadf8698.

PMID: 37205756 PMC: 10198629. DOI: 10.1126/sciadv.adf8698.

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit.

Milligan L, Sayou C, Tuck A, Auchynnikava T, Reid J, Alexander R Elife. 2017; 6.

PMID: 29027900 PMC: 5673307. DOI: 10.7554/eLife.27082.

The RNA polymerase II CTD "orphan" residues: Emerging insights into the functions of Tyr-1, Thr-4, and Ser-7.

Yurko N, Manley J Transcription. 2017; 9(1):30-40.

PMID: 28771071 PMC: 5791814. DOI: 10.1080/21541264.2017.1338176.

References

Chesnut J, Stephens J, Dahmus M . The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa. J Biol Chem. 1992; 267(15):10500-6. View

Laybourn P, Dahmus M . Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription. J Biol Chem. 1990; 265(22):13165-73. View

Bartholomew B, Dahmus M, Meares C . RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes. J Biol Chem. 1986; 261(30):14226-31. View

Cadena D, Dahmus M . Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II. J Biol Chem. 1987; 262(26):12468-74. View