Joan W Conaway
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Explore the profile of Joan W Conaway including associated specialties, affiliations and a list of published articles.
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76
Citations
4431
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Recent Articles
11.
Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, et al.
Nat Commun
. 2020 Feb;
11(1):1063.
PMID: 32102997
Mediator is a coregulatory complex that regulates transcription of Pol II-dependent genes. Previously, we showed that human Mediator subunit MED26 plays a role in the recruitment of Super Elongation Complex...
12.
Conaway R, Conaway J
Nat Struct Mol Biol
. 2019 Aug;
26(9):771-776.
PMID: 31439940
The discovery of the three eukaryotic nuclear RNA polymerases paved the way for serious biochemical investigations of eukaryotic transcription and the identification of eukaryotic transcription factors. Here we describe this...
13.
Tettey T, Gao X, Shao W, Li H, Story B, Chitsazan A, et al.
Cell Rep
. 2019 Jun;
27(13):3770-3779.e7.
PMID: 31242411
FACT (facilitates chromatin transcription) is an evolutionarily conserved histone chaperone that was initially identified as an activity capable of promoting RNA polymerase II (Pol II) transcription through nucleosomes in vitro....
14.
Noe Gonzalez M, Conaway J, Conaway R
J Vis Exp
. 2019 May;
(147).
PMID: 31132066
Eukaryotic mRNA synthesis is a complex biochemical process requiring transcription of a DNA template into a precursor RNA by the multi-subunit enzyme RNA polymerase II and co-transcriptional capping and splicing...
15.
Wang L, He Y, Li M, Ding J, Sui Y, Conaway J, et al.
Protein Cell
. 2019 May;
10(9):694-699.
PMID: 31111444
No abstract available.
16.
Weems J, Unruh J, Slaughter B, Conaway R, Conaway J
Methods
. 2019 Feb;
159-160:157-164.
PMID: 30794906
Elongin A binds to Elongins B and C to form the RNA polymerase II transcription elongation factor Elongin. It also functions as the substrate recognition subunit of a ubiquitin ligase...
17.
Noe Gonzalez M, Conaway R, Conaway J
Mol Cell
. 2018 Dec;
72(5):802-804.
PMID: 30526870
In a recent publication in Science, Kujirai et al. (2018) use single-particle cryo-EM to resolve several Pol II-nucleosome interactions, shedding new light on transcription elongation in a native chromatin environment.
18.
Noe Gonzalez M, Sato S, Tomomori-Sato C, Conaway J, Conaway R
Nat Commun
. 2018 Aug;
9(1):3392.
PMID: 30139934
Co-transcriptional capping of RNA polymerase II (Pol II) transcripts by capping enzyme proceeds orders of magnitude more efficiently than capping of free RNA. Previous studies brought to light a role...
19.
Gopalan S, Gibbon D, Banks C, Zhang Y, Florens L, Washburn M, et al.
Nucleic Acids Res
. 2018 Aug;
46(19):10095-10105.
PMID: 30102332
ELL family transcription factors activate the overall rate of RNA polymerase II (Pol II) transcription elongation by binding directly to Pol II and suppressing its tendency to pause. In metazoa,...
20.
Tsai K, Tomomori-Sato C, Sato S, Conaway R, Conaway J, Asturias F
Cell
. 2017 Sep;
158(2):463.
PMID: 28915369
No abstract available.