Jianwei Hou
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Explore the profile of Jianwei Hou including associated specialties, affiliations and a list of published articles.
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18
Citations
549
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Recent Articles
11.
Yang Y, Yang Y, Hou J, Ding Y, Zhang T, Zhang Y, et al.
PLoS One
. 2016 Jan;
11(1):e0147026.
PMID: 26771380
Genipin (GNP) effectively inhibits uncoupling protein 2 (UCP2), which regulates the leakage of protons across the inner mitochondrial membrane. UCP2 inhibition may induce pancreatic adenocarcinoma cell death by increasing reactive...
12.
Siddiq M, Hannila S, Carmel J, Bryson J, Hou J, Nikulina E, et al.
J Biol Chem
. 2015 May;
290(26):16343-56.
PMID: 25947372
The adult CNS does not spontaneously regenerate after injury, due in large part to myelin-associated inhibitors such as myelin-associated glycoprotein (MAG), Nogo-A, and oligodendrocyte-myelin glycoprotein. All three inhibitors can interact...
13.
Martinez J, Stessin A, Campana A, Hou J, Nikulina E, Buck J, et al.
J Neurosci
. 2014 Jul;
34(28):9281-9.
PMID: 25009261
Neurons in the CNS do not regenerate following injury; regeneration is blocked by inhibitory proteins in myelin, such as myelin-associated glycoprotein (MAG). Elevating neuronal levels of the second messenger cAMP...
14.
Hannila S, Siddiq M, Carmel J, Hou J, Chaudhry N, Bradley P, et al.
J Neurosci
. 2013 Mar;
33(12):5138-51.
PMID: 23516280
After CNS injury, axonal regeneration is limited by myelin-associated inhibitors; however, this can be overcome through elevation of intracellular cyclic AMP (cAMP), as occurs with conditioning lesions of the sciatic...
15.
Tang M, Shu W, Yang F, Zhang J, Dong G, Hou J
Nanotechnology
. 2009 Aug;
20(38):385602.
PMID: 19713590
Bismuth titanates with La-substituted (Bi(3.25)La(0.75)Ti(3)O(12), BLT) nanofibers were synthesized by sol-gel based electrospinning. Pure phase perovskite structure BLT nanofibers could be obtained by annealing at 700 degrees C in air...
16.
Cao Z, Qiu J, Domeniconi M, Hou J, Bryson J, Mellado W, et al.
J Neurosci
. 2007 Aug;
27(34):9146-54.
PMID: 17715351
Myelin-associated glycoprotein (MAG) is a potent inhibitor of axonal regeneration. It contains five Ig-like domains and is a sialic binding protein. Previously, we showed that the sialic acid binding site...
17.
Cao Z, Gao Y, Bryson J, Hou J, Chaudhry N, Siddiq M, et al.
J Neurosci
. 2006 May;
26(20):5565-73.
PMID: 16707807
Lesioning the peripheral branch of a dorsal root ganglion (DRG) neuron before injury of the central branch of the same neuron enables spontaneous regeneration of these spinal axons. This effect...
18.
Gao Y, Deng K, Hou J, Bryson J, Barco A, Nikulina E, et al.
Neuron
. 2004 Nov;
44(4):609-21.
PMID: 15541310
Inhibitors in myelin play a major role in preventing spontaneous axonal regeneration after CNS injury. Elevation of cAMP overcomes this inhibition, in a transcription-dependent manner, through the upregulation of Arginase...
19.
Wang S, Cai Q, Hou J, Bei J, Zhang T, Yang J, et al.
J Biomed Mater Res A
. 2003 Aug;
66(3):522-31.
PMID: 12918035
In this study, nerve guides composed of poly(D,L-lactide) (PDLLA) were fabricated and used in the repair of transected sciatic nerves (15-mm gaps) of rats. Nerve guides with a two-ply structure...