Jerome Audoux
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Explore the profile of Jerome Audoux including associated specialties, affiliations and a list of published articles.
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11
Citations
131
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Recent Articles
1.
Boidot R, Blum M, Wissler M, Gottin C, Ruzicka J, Chevrier S, et al.
Eur J Cancer
. 2024 Mar;
202:113978.
PMID: 38471290
Background: The PAOLA-1/ENGOT-ov25 trial showed that maintenance olaparib plus bevacizumab increases survival of advanced ovarian cancer patients with homologous recombination deficiency (HRD). However, decentralized solutions to test for HRD in...
2.
Yauy K, Lecoquierre F, Baert-Desurmont S, Trost D, Boughalem A, Luscan A, et al.
Genet Med
. 2022 Mar;
24(6):1316-1327.
PMID: 35311657
Purpose: Retrospective interpretation of sequenced data in light of the current literature is a major concern of the field. Such reinterpretation is manual and both human resources and variable operating...
3.
Riquier S, Bessiere C, Guibert B, Bouge A, Boureux A, Ruffle F, et al.
NAR Genom Bioinform
. 2021 Jun;
3(3):lqab058.
PMID: 34179780
The huge body of publicly available RNA-sequencing (RNA-seq) libraries is a treasure of functional information allowing to quantify the expression of known or novel transcripts in tissues. However, transcript quantification...
4.
Ruffle F, Audoux J, Boureux A, Beaumeunier S, Gaillard J, Samra E, et al.
F1000Res
. 2018 Apr;
6.
PMID: 29623188
High-throughput next generation sequencing (NGS) technologies enable the detection of biomarkers used for tumor classification, disease monitoring and cancer therapy. Whole-transcriptome analysis using RNA-seq is important, not only as a...
5.
Bouge A, Ruffle F, Riquier S, Guibert B, Audoux J, Commes T
Methods Mol Biol
. 2018 Mar;
1769:133-156.
PMID: 29564822
RNA-Seq approach enables the detection and characterization of fusion or chimeric transcript associated to complex genome rearrangement. Until now, these events are classically identified at DNA level.Here we describe a...
6.
Audoux J, Philippe N, Chikhi R, Salson M, Gallopin M, Gabriel M, et al.
Genome Biol
. 2017 Dec;
18(1):243.
PMID: 29284518
We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with...
7.
Hooks K, Audoux J, Fazli H, Lesjean S, Ernault T, Dugot-Senant N, et al.
Hepatology
. 2017 Nov;
68(1):89-102.
PMID: 29152775
Conclusion: The highly proliferating C2A subtype is characterized by topoisomerase 2-alpha gene up-regulation and FA pathway activation, and the HB therapeutic arsenal could include bortezomib for the treatment of patients...
8.
Audoux J, Salson M, Grosset C, Beaumeunier S, Holder J, Commes T, et al.
BMC Bioinformatics
. 2017 Oct;
18(1):428.
PMID: 28969586
Background: The evolution of next-generation sequencing (NGS) technologies has led to increased focus on RNA-Seq. Many bioinformatic tools have been developed for RNA-Seq analysis, each with unique performance characteristics and...
9.
Beaumeunier S, Audoux J, Boureux A, Ruffle F, Commes T, Philippe N, et al.
BioData Min
. 2016 Nov;
9:34.
PMID: 27822312
Background: High-throughput sequencing technology and bioinformatics have identified chimeric RNAs (chRNAs), raising the possibility of chRNAs expressing particularly in diseases can be used as potential biomarkers in both diagnosis and...
10.
Doucet A, Droc G, Siol O, Audoux J, Gilbert N
Mol Biol Evol
. 2015 Mar;
32(7):1815-32.
PMID: 25761766
Transposable elements comprise more than 45% of the human genome and long interspersed nuclear element 1 (LINE-1 or L1) is the only autonomous mobile element remaining active. Since its identification,...