Jeremy C Allegood
Overview
Explore the profile of Jeremy C Allegood including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
3643
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Bogaard H, Mizuno S, Guignabert C, Al Hussaini A, Farkas D, Ruiter G, et al.
Am J Respir Cell Mol Biol
. 2011 Dec;
46(5):582-91.
PMID: 22162909
Obliteration of the vascular lumen by endothelial cell growth is a hallmark of many forms of severe pulmonary arterial hypertension. Copper plays a significant role in the control of endothelial...
22.
Lepine S, Allegood J, Edmonds Y, Milstien S, Spiegel S
J Biol Chem
. 2011 Nov;
286(52):44380-90.
PMID: 22052905
Sphingosine 1-phosphate (S1P) and ceramide have been implicated in both autophagy and apoptosis. However, the roles of these sphingolipid metabolites in the links between these two processes are not completely...
23.
Haynes C, Allegood J, Wang E, Kelly S, Sullards M, Merrill Jr A
J Lipid Res
. 2011 May;
52(8):1583-94.
PMID: 21586681
This study describes the use of a stable-isotope labeled precursor ([U-¹³C]palmitate) to analyze de novo sphingolipid biosynthesis by tandem mass spectrometry. It also describes factors to consider in interpreting the...
24.
Symolon H, Bushnev A, Peng Q, Ramaraju H, Mays S, Allegood J, et al.
Mol Cancer Ther
. 2011 Mar;
10(4):648-57.
PMID: 21398423
Sphingoid bases are cytotoxic for many cancer cell lines and are thought to contribute to suppression of intestinal tumorigenesis in vivo by ingested sphingolipids. This study explored the behavior of...
25.
Strub G, Paillard M, Liang J, Gomez L, Allegood J, Hait N, et al.
FASEB J
. 2010 Oct;
25(2):600-12.
PMID: 20959514
The potent lipid mediator sphingosine-1-phosphate (S1P) regulates diverse physiological processes by binding to 5 specific GPCRs, although it also has intracellular targets. Here, we demonstrate that S1P, produced in the...
26.
Sims K, Haynes C, Kelly S, Allegood J, Wang E, Momin A, et al.
J Biol Chem
. 2010 Sep;
285(49):38568-79.
PMID: 20876532
Activation of RAW264.7 cells with a lipopolysaccharide specific for the TLR4 receptor, Kdo(2)-lipid A (KLA), causes a large increase in cellular sphingolipids, from 1.5 to 2.6 × 10(9) molecules per...
27.
Takabe K, Kim R, Allegood J, Mitra P, Ramachandran S, Nagahashi M, et al.
J Biol Chem
. 2010 Jan;
285(14):10477-86.
PMID: 20110355
Sphingosine 1-phosphate (S1P), a potent sphingolipid mediator produced by sphingosine kinase isoenzymes (SphK1 and SphK2), regulates diverse cellular processes important for breast cancer progression acting in an autocrine and/or paracrine...
28.
Sauane M, Su Z, Dash R, Liu X, Norris J, Sarkar D, et al.
J Cell Physiol
. 2009 Nov;
222(3):546-55.
PMID: 19937735
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24) uniquely displays broad cancer-specific apoptosis-inducing activity through induction of endoplasmic reticulum (ER) stress. We hypothesize that ceramide, a promoter of apoptosis, might contribute to mda-7/IL-24...
29.
Kapitonov D, Allegood J, Mitchell C, Hait N, Almenara J, Adams J, et al.
Cancer Res
. 2009 Sep;
69(17):6915-23.
PMID: 19723667
Sphingosine-1-phosphate is a potent sphingolipid mediator of diverse processes important for brain tumors, including cell growth, survival, migration, invasion, and angiogenesis. Sphingosine kinase 1 (SphK1), one of the two isoenzymes...
30.
Wijesinghe D, Allegood J, Gentile L, Fox T, Kester M, Chalfant C
J Lipid Res
. 2009 Aug;
51(3):641-51.
PMID: 19654423
Ceramide-1-phosphate (C1P) is a bioactive sphingolipid with roles in several biological processes. Currently, high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC ESI-MS/MS) offers the most efficient method of quantifying C1P....