Jeremy C Allegood
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Explore the profile of Jeremy C Allegood including associated specialties, affiliations and a list of published articles.
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46
Citations
3643
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Recent Articles
11.
Oyeniran C, Sturgill J, Hait N, Huang W, Avni D, Maceyka M, et al.
J Allergy Clin Immunol
. 2015 Apr;
136(4):1035-46.e6.
PMID: 25842287
Background: Asthma, a chronic inflammatory condition defined by episodic shortness of breath with expiratory wheezing and cough, is a serious health concern affecting more than 250 million persons. Genome-wide association...
12.
Nagahashi M, Takabe K, Liu R, Peng K, Wang X, Wang Y, et al.
Hepatology
. 2014 Nov;
61(4):1216-26.
PMID: 25363242
Unlabelled: Bile acids are important hormones during the feed/fast cycle, allowing the liver to coordinately regulate nutrient metabolism. How they accomplish this has not been fully elucidated. Conjugated bile acids...
13.
Aluri H, Simpson D, Allegood J, Hu Y, Szczepanek K, Gronert S, et al.
Biochim Biophys Acta
. 2014 Aug;
1840(11):3199-207.
PMID: 25092652
Background: Cytochrome c (Cyt c) is a mobile component of the electron transport chain (ETC.) which contains a tightly coordinated heme iron. In pathologic settings, a key ligand of the...
14.
Hait N, Wise L, Allegood J, OBrien M, Avni D, Reeves T, et al.
Nat Neurosci
. 2014 May;
17(7):971-80.
PMID: 24859201
FTY720 (fingolimod), an FDA-approved drug for treatment of multiple sclerosis, has beneficial effects in the CNS that are not yet well understood, independent of its effects on immune cell trafficking....
15.
Kondo S, Bottos A, Allegood J, Masson R, Maurer F, Genoud C, et al.
PLoS One
. 2014 Apr;
9(4):e94114.
PMID: 24714781
Memo is a conserved protein that was identified as an essential mediator of tumor cell motility induced by receptor tyrosine kinase activation. Here we show that Memo null mouse embryonic...
16.
Harikumar K, Yester J, Surace M, Oyeniran C, Price M, Huang W, et al.
Nat Immunol
. 2014 Jan;
15(3):231-8.
PMID: 24464131
Although interleukin 1 (IL-1) induces expression of the transcription factor IRF1 (interferon-regulatory factor 1), the roles of IRF1 in immune and inflammatory responses and mechanisms of its activation remain elusive....
17.
Liang J, Nagahashi M, Kim E, Harikumar K, Yamada A, Huang W, et al.
Cancer Cell
. 2013 Jan;
23(1):107-20.
PMID: 23273921
Inflammatory bowel disease is an important risk factor for colorectal cancer. We show that sphingosine-1-phosphate (S1P) produced by upregulation of sphingosine kinase 1 (SphK1) links chronic intestinal inflammation to colitis-associated...
18.
Nagahashi M, Kim E, Yamada A, Ramachandran S, Allegood J, Hait N, et al.
FASEB J
. 2012 Nov;
27(3):1001-11.
PMID: 23180825
Sphingosine-1-phosphate (S1P), a ligand for 5 specific receptors, is a potent lipid mediator that plays important roles in lymphocyte trafficking and immune responses. S1P is produced inside cells and therefore...
19.
Price M, Oskeritzian C, Falanga Y, Harikumar K, Allegood J, Alvarez S, et al.
J Allergy Clin Immunol
. 2012 Sep;
131(2):501-11.e1.
PMID: 22939756
Background: Sphingosine-1-phosphate (S1P), which is produced by 2 sphingosine kinase (SphK) isoenzymes, SphK1 and SphK2, has been implicated in IgE-mediated mast cell responses. However, studies of allergic inflammation in isotype-specific...
20.
Nagahashi M, Ramachandran S, Kim E, Allegood J, Rashid O, Yamada A, et al.
Cancer Res
. 2012 Feb;
72(3):726-35.
PMID: 22298596
Sphingosine-1-phosphate (S1P) is a pleiotropic bioactive lipid mediator that promotes breast cancer progression by diverse mechanisms that remain somewhat unclear. Here we report pharmacologic evidence of a critical role for...