Jeremy C Allegood
Overview
Explore the profile of Jeremy C Allegood including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
3643
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0
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Recent Articles
1.
Jones B, Myakala K, Guha M, Davidson S, Adapa S, Lopez Santiago I, et al.
Am J Physiol Renal Physiol
. 2023 Oct;
325(6):F792-F810.
PMID: 37823198
Farnesoid X receptor (FXR) activation reduces renal inflammation, but the underlying mechanisms remain elusive. Neutrophil extracellular traps (NETs) are webs of DNA formed when neutrophils undergo specialized programmed cell death...
2.
Pierre-Louis Odoom J, Freeberg M, Camus S, Toft R, Szomju B, Sanchez Rosado R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Apr;
324(6):L863-L869.
PMID: 37039378
Radiation-induced lung injury (RILI) is a consequence of therapeutic thoracic irradiation (TR) for many cancers, and there are no FDA-approved curative strategies. Studies report that 80% of patients who undergo...
3.
Wilkerson J, Basu S, Stiles M, Prislovsky A, Grambergs R, Nicholas S, et al.
Cells
. 2022 Sep;
11(18).
PMID: 36139489
The purpose of this study was to investigate the role of sphingosine kinase 1 (SphK1), which generates sphingosine-1-phosphate (S1P), in corneal neovascularization (NV) Wild-type (WT) and knockout () mice received...
4.
Javaheri A, Allegood J, Cowart L, Chirinos J
J Am Coll Cardiol
. 2020 May;
75(17):2273-2275.
PMID: 32354389
No abstract available.
5.
Mohammed S, Vineetha N, James S, Aparna J, Babu Lankadasari M, Allegood J, et al.
FASEB J
. 2019 Mar;
33(6):7061-7071.
PMID: 30840833
Systemic lupus erythematosus is an autoimmune disease characterized by overproduction of type 1 IFN that causes multiple organ dysfunctions. Plasmacytoid dendritic cells (pDCs) that secrete large amounts of IFN have...
6.
Wilmott L, Grambergs R, Allegood J, Lyons T, Mandal N
J Diabetes Complications
. 2019 Jan;
33(3):195-201.
PMID: 30630661
Objective: Sphingolipids have a fundamental role in many cellular processes, and they have been implicated in insulin resistance and Diabetes Mellitus (DM) and its complications, including diabetic retinopathy (DR). Little...
7.
Montefusco D, Allegood J, Spiegel S, Cowart L
Biochem Biophys Res Commun
. 2018 May;
504(3):608-616.
PMID: 29778532
Non-alcoholic fatty liver disease (NAFLD) is a major clinical concern and its treatment consumes abundant resources. While accumulation of lipids in hepatocytes initiates the disease, this in itself is not...
8.
Nagahashi M, Yamada A, Katsuta E, Aoyagi T, Huang W, Terracina K, et al.
Cancer Res
. 2018 Jan;
78(7):1713-1725.
PMID: 29351902
Although obesity with associated inflammation is now recognized as a risk factor for breast cancer and distant metastases, the functional basis for these connections remain poorly understood. Here, we show...
9.
Rizzo J, Colombo A, Zamith-Miranda D, Silva V, Allegood J, Casadevall A, et al.
Biochim Biophys Acta Mol Cell Res
. 2018 Jan;
1865(3):532-541.
PMID: 29291962
Flippases are responsible for the asymmetric distribution of phospholipids in biological membranes. In the encapsulated fungal pathogen Cryptococcus neoformans, the putative flippase Apt1 is an important regulator of polysaccharide secretion...
10.
Nagahashi M, Yamada A, Miyazaki H, Allegood J, Tsuchida J, Aoyagi T, et al.
J Mammary Gland Biol Neoplasia
. 2016 May;
21(1-2):9-17.
PMID: 27194029
The tumor microenvironment is a determining factor for cancer biology and progression. Sphingosine-1-phosphate (S1P), produced by sphingosine kinases (SphKs), is a bioactive lipid mediator that regulates processes important for cancer...