Jens Peter von Kries
Overview
Explore the profile of Jens Peter von Kries including associated specialties, affiliations and a list of published articles.
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55
Citations
1386
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Recent Articles
21.
Specker E, Matthes S, Wesolowski R, Schutz A, Grohmann M, Alenina N, et al.
J Med Chem
. 2022 Aug;
65(16):11126-11149.
PMID: 35921615
Tryptophan hydroxylases catalyze the first and rate-limiting step in the synthesis of serotonin. Serotonin is a key neurotransmitter in the central nervous system and, in the periphery, functions as a...
22.
Walker-Gray R, Pallien T, Miller D, Oder A, Neuenschwander M, von Kries J, et al.
Methods Mol Biol
. 2022 Mar;
2483:117-139.
PMID: 35286673
A-kinase anchoring proteins (AKAPs) are a family of multivalent scaffolding proteins. They engage in direct protein-protein interactions with protein kinases, kinase substrates and further signaling molecules. Each AKAP interacts with...
23.
Baltzer S, Bulatov T, Schmied C, Kramer A, Berger B, Oder A, et al.
Int J Mol Sci
. 2022 Jan;
23(2).
PMID: 35054947
The cAMP-dependent aquaporin-2 (AQP2) redistribution from intracellular vesicles into the plasma membrane of renal collecting duct principal cells induces water reabsorption and fine-tunes body water homeostasis. However, the mechanisms controlling...
24.
Ostrop J, Zwiggelaar R, Pedersen M, Gerbe F, Bosl K, Lindholm H, et al.
Front Cell Dev Biol
. 2021 Feb;
8:618552.
PMID: 33575256
Intestinal organoids are an excellent model to study epithelial biology. Yet, the selection of analytical tools to accurately quantify heterogeneous organoid cultures remains limited. Here, we developed a semi-automated organoid...
25.
Mostinski Y, Heynen G, Lopez-Alberca M, Paul J, Miksche S, Radetzki S, et al.
J Med Chem
. 2020 Nov;
63(23):14780-14804.
PMID: 33210922
The tyrosine phosphatase SHP2 controls the activity of pivotal signaling pathways, including MAPK, JAK-STAT, and PI3K-Akt. Aberrant SHP2 activity leads to uncontrolled cell proliferation, tumorigenesis, and metastasis. SHP2 signaling was...
26.
Kircher T, Pantsar T, Oder A, von Kries J, Juchum M, Pfaffenrot B, et al.
Eur J Med Chem
. 2020 Oct;
209:112901.
PMID: 33092905
The mitogen-activated protein kinase kinase 4 (MKK4) plays a key role in liver regeneration and is under investigation as a target for stimulating hepatocytes to increased proliferation. Therefore, new small...
27.
Dema A, Faust D, Lazarow K, Wippich M, Neuenschwander M, Zuhlke K, et al.
Cells
. 2020 Mar;
9(3).
PMID: 32164329
Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2). The hormone binds to vasopressin V2 receptors (V2R) on the surface...
28.
Yusenko M, Trentmann A, Andersson M, Abdel Ghani L, Jakobs A, Arteaga Paz M, et al.
Cancer Lett
. 2020 Feb;
479:61-70.
PMID: 32014461
The master transcriptional regulator MYB is a key oncogenic driver in several human neoplasms, particularly in acute myeloid leukemia (AML) and adenoid cystic carcinoma (ACC). MYB is therefore an attractive...
29.
Ullrich F, Blin S, Lazarow K, Daubitz T, von Kries J, Jentsch T
Elife
. 2019 Jul;
8.
PMID: 31318332
Acid-sensing ion channels have important functions in physiology and pathology, but the molecular composition of acid-activated chloride channels had remained unclear. We now used a genome-wide siRNA screen to molecularly...
30.
Marcinkowski P, Hoyer I, Specker E, Furkert J, Rutz C, Neuenschwander M, et al.
Thyroid
. 2018 Oct;
29(1):111-123.
PMID: 30351237
Background: The thyrotropin receptor (TSHR) is the target for autoimmune thyroid stimulating antibodies (TSAb) triggering hyperthyroidism. Whereas elevated thyroid hormone synthesis by the thyroid in Graves' disease can be treated...