Jean-Yves Roignant
Overview
Explore the profile of Jean-Yves Roignant including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
47
Citations
2008
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Diensthuber G, Pryszcz L, Llovera L, Lucas M, Delgado-Tejedor A, Cruciani S, et al.
Genome Res
. 2024 Sep;
34(11):1865-1877.
PMID: 39271295
In recent years, nanopore direct RNA sequencing (DRS) became a valuable tool for studying the epitranscriptome, owing to its ability to detect multiple modifications within the same full-length native RNA...
2.
Guillen-Angel M, Roignant J
Curr Opin Genet Dev
. 2024 Jun;
87:102210.
PMID: 38833893
Pseudouridine (Ψ), the most abundant RNA modification, plays a role in pre-mRNA splicing, RNA stability, protein translation efficiency, and cellular responses to environmental stress. Dysregulation of pseudouridylation is linked to...
3.
Lavergne G, Roignant J
Mol Cell
. 2024 May;
84(9):1631-1632.
PMID: 38701738
In this issue of Molecular Cell, Hao et al. demonstrate that the RNA helicase DDX21 recruits the mA methyltransferase complex to R-loops, ensuring proper transcription termination and genome stability.
4.
Sklias A, Cruciani S, Marchand V, Spagnuolo M, Lavergne G, Bourguignon V, et al.
Nucleic Acids Res
. 2024 Feb;
52(6):2848-2864.
PMID: 38416577
During their maturation, ribosomal RNAs (rRNAs) are decorated by hundreds of chemical modifications that participate in proper folding of rRNA secondary structures and therefore in ribosomal function. Along with pseudouridine,...
5.
Rathore O, Silva R, Ascensao-Ferreira M, Matos R, Carvalho C, Marques B, et al.
RNA
. 2023 Dec;
30(1):99.
PMID: 38110224
No abstract available.
6.
Helm M, Bohnsack M, Carell T, Dalpke A, Entian K, Ehrenhofer-Murray A, et al.
ACS Chem Biol
. 2023 Nov;
18(12):2441-2449.
PMID: 37962075
The chemical biology of native nucleic acid modifications has seen an intense upswing, first concerning DNA modifications in the field of epigenetics and then concerning RNA modifications in a field...
7.
Lee S, Koo B, Carre C, Fischer A, He C, Kumar A, et al.
Front Neurosci
. 2023 Nov;
17:1291446.
PMID: 37928731
Increasing evidence reinforces the essential function of RNA modifications in development and diseases, especially in the nervous system. RNA modifications impact various processes in the brain, including neurodevelopment, neurogenesis, neuroplasticity,...
8.
Mattioli F, Worpenberg L, Li C, Ibrahim N, Naz S, Sharif S, et al.
Genet Med
. 2023 May;
25(9):100900.
PMID: 37226891
Purpose: 5-methylcytosine RNA modifications are driven by NSUN methyltransferases. Although variants in NSUN2 and NSUN3 were associated with neurodevelopmental diseases, the physiological role of NSUN6 modifications on transfer RNAs and...
9.
Brazane M, Dimitrova D, Pigeon J, Paolantoni C, Ye T, Marchand V, et al.
Life Sci Alliance
. 2023 Jan;
6(4).
PMID: 36720500
FTSJ1 is a conserved human 2'-O-methyltransferase (Nm-MTase) that modifies several tRNAs at position 32 and the wobble position 34 in the anticodon loop. Its loss of function has been linked...
10.
Lavergne G, Roignant J
Mol Cell
. 2022 Jun;
82(11):1979-1980.
PMID: 35659324
Viegas et al. (2022) discover that in Trypanosoma brucei the poly(A) tails of the variant surface glycoprotein (VSG) transcripts are methylated, a mechanism that stabilizes these transcripts and ensures protection...