Jay W Schneider
Overview
Explore the profile of Jay W Schneider including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
2781
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0
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Recent Articles
1.
Clemens D, Ye D, Zhou W, Kim C, Pease D, Navaratnarajah C, et al.
PLoS One
. 2023 Mar;
18(3):e0282151.
PMID: 36888581
Background: SARS-CoV-2-mediated COVID-19 may cause sudden cardiac death (SCD). Factors contributing to this increased risk of potentially fatal arrhythmias include thrombosis, exaggerated immune response, and treatment with QT-prolonging drugs. However,...
2.
Navaratnarajah C, Pease D, Halfmann P, Taye B, Barkhymer A, Howell K, et al.
J Virol
. 2021 Oct;
95(24):e0136821.
PMID: 34613786
Severe cardiovascular complications can occur in coronavirus disease of 2019 (COVID-19) patients. Cardiac damage is attributed mostly to the aberrant host response to acute respiratory infection. However, direct infection of...
3.
Schneider J, Oommen S, Qureshi M, Goetsch S, Pease D, Sundsbak R, et al.
Nat Med
. 2021 Jun;
27(7):1309.
PMID: 34079106
No abstract available.
4.
Schneider J, Oommen S, Qureshi M, Goetsch S, Pease D, Sundsbak R, et al.
Nat Med
. 2020 Nov;
26(11):1788-1800.
PMID: 33188278
Ribonucleoprotein (RNP) granules are biomolecular condensates-liquid-liquid phase-separated droplets that organize and manage messenger RNA metabolism, cell signaling, biopolymer assembly, biochemical reactions and stress granule responses to cellular adversity. Dysregulated RNP...
5.
Zheng C, Schneider J, Hsieh J
Dev Biol
. 2020 Mar;
462(2):197-207.
PMID: 32197890
Three-dimensional (3D) organoid models derived from human pluripotent stem cells provide a platform for studying human development and understanding disease mechanisms. Most studies that examine biallelic inactivation of the cell...
6.
Altamirano F, Schiattarella G, French K, Kim S, Engelberger F, Kyrychenko S, et al.
Circulation
. 2019 Jun;
140(11):921-936.
PMID: 31220931
Background: Polycystin-1 (PC1) is a transmembrane protein originally identified in autosomal dominant polycystic kidney disease where it regulates the calcium-permeant cation channel polycystin-2. Autosomal dominant polycystic kidney disease patients develop...
7.
Long C, Li H, Tiburcy M, Rodriguez-Caycedo C, Kyrychenko V, Zhou H, et al.
Sci Adv
. 2018 Feb;
4(1):eaap9004.
PMID: 29404407
Genome editing with CRISPR/Cas9 is a promising new approach for correcting or mitigating disease-causing mutations. Duchenne muscular dystrophy (DMD) is associated with lethal degeneration of cardiac and skeletal muscle caused...
8.
Parra V, Altamirano F, Hernandez-Fuentes C, Tong D, Kyrychenko V, Rotter D, et al.
Circ Res
. 2018 Jan;
122(6):e20-e33.
PMID: 29362227
Rationale: The regulator of calcineurin 1 (RCAN1) inhibits CN (calcineurin), a Ca-activated protein phosphatase important in cardiac remodeling. In humans, is located on chromosome 21 in proximity to the Down...
9.
Meng X, Arning E, Wight-Carter M, Day T, Jabbarzadeh-Tabrizi S, Chen S, et al.
J Inherit Metab Dis
. 2017 Nov;
41(2):231-238.
PMID: 29110178
Fabry disease is a glycosphingolipidosis caused by deficient activity of α-galactosidase A; it is one of a few diseases that are associated with priapism, an abnormal prolonged erection of the...
10.
Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton J, Long C, Schneider J, et al.
JCI Insight
. 2017 Sep;
2(18).
PMID: 28931764
Dystrophin maintains the integrity of striated muscles by linking the actin cytoskeleton with the cell membrane. Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene (DMD) that...