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Jason R Myers

Explore the profile of Jason R Myers including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 1926
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Recent Articles
11.
Chavez J, Rabe J, Loeffler D, Higa K, Hernandez G, Mills T, et al.
J Exp Med . 2021 Apr; 218(6). PMID: 33857288
Hematopoietic stem cells (HSCs) are capable of entering the cell cycle to replenish the blood system in response to inflammatory cues; however, excessive proliferation in response to chronic inflammation can...
12.
Burke C, Myers J, Post C, Boule L, Lawrence B
Environ Health Perspect . 2021 Jan; 129(1):17007. PMID: 33449811
Background: Early life environmental exposures can have lasting effects on the function of the immune system and contribute to disease later in life. Epidemiological studies have linked early life exposure...
13.
Wu J, Subbaiah K, Xie L, Jiang F, Khor E, Mickelsen D, et al.
Circ Res . 2020 Jul; 127(6):827-846. PMID: 32611237
Rationale: Increased protein synthesis of profibrotic genes is a common feature in cardiac fibrosis and heart failure. Despite this observation, critical factors and molecular mechanisms for translational control of profibrotic...
14.
Pei S, Pollyea D, Gustafson A, Stevens B, Minhajuddin M, Fu R, et al.
Cancer Discov . 2020 Jan; 10(4):536-551. PMID: 31974170
Venetoclax-based therapy can induce responses in approximately 70% of older previously untreated patients with acute myeloid leukemia (AML). However, up-front resistance as well as relapse following initial response demonstrates the...
15.
Azadniv M, Myers J, McMurray H, Guo N, Rock P, Coppage M, et al.
Leukemia . 2019 Sep; 34(2):391-403. PMID: 31492897
Bone marrow mesenchymal stromal cells (MSCs) constitute one of the important components of the hematopoietic microenvironmental niche. In vivo studies have shown that depletion of marrow MSCs resulted in reduction...
16.
Burke C, Myers J, Boule L, Post C, Brookes P, Lawrence B
Sci Rep . 2019 Aug; 9(1):11489. PMID: 31391494
Early life environmental exposures drive lasting changes to the function of the immune system and can contribute to disease later in life. One of the ways environmental factors act is...
17.
Franchini A, Myers J, Jin G, Shepherd D, Lawrence B
Immunohorizons . 2019 Jul; 3(6):219-235. PMID: 31356168
Activation of the ligand inducible aryl hydrocarbon receptor (AhR) during primary influenza A virus infection diminishes host responses by negatively regulating the ability of dendritic cells (DC) to prime naive...
18.
Hernandez G, Mills T, Rabe J, Chavez J, Kuldanek S, Kirkpatrick G, et al.
Haematologica . 2019 May; 105(3):585-597. PMID: 31101752
Rheumatoid arthritis (RA) is a debilitating autoimmune disease characterized by chronic inflammation and progressive destruction of joint tissue. It is also characterized by aberrant blood phenotypes including anemia and suppressed...
19.
Adane B, Ye H, Khan N, Pei S, Minhajuddin M, Stevens B, et al.
Cell Rep . 2019 Apr; 27(1):238-254.e6. PMID: 30943405
The NADPH-dependent oxidase NOX2 is an important effector of immune cell function, and its activity has been linked to oncogenic signaling. Here, we describe a role for NOX2 in leukemia-initiating...
20.
Wang Q, Bhattacharya S, Mereness J, Anderson C, Lillis J, Misra R, et al.
Pediatr Res . 2019 Feb; 87(3):511-517. PMID: 30776794
Background: Current in vitro human lung epithelial cell models derived from adult tissues may not accurately represent all attributes that define homeostatic and disease mechanisms relevant to the pediatric lung....