Thomas J Mariani
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Explore the profile of Thomas J Mariani including associated specialties, affiliations and a list of published articles.
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112
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3488
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Recent Articles
1.
Osborn R, Anderson C, Leach J, Chu C, Dewhurst S, Mariani T, et al.
Clin Exp Immunol
. 2025 Jan;
PMID: 39780400
Introduction: The ability of SARS-CoV-2 to evade antiviral immune signaling in the airway contributes to the severity of COVID-19 disease. Additionally, COVID-19 is influenced by age and has more severe...
2.
Ushakumary M, Feng S, Bandyopadhyay G, Olson H, Weitz K, Huyck H, et al.
Am J Respir Cell Mol Biol
. 2024 Oct;
PMID: 39447176
The lung is a vital organ that undergoes extensive morphological and functional changes during postnatal development. To disambiguate how different cell populations contribute to organ development, we performed proteomic and...
3.
Bender W, Zhang Y, Corbett A, Chu C, Grier A, Wang L, et al.
BMC Med Genomics
. 2024 Jun;
17(1):165.
PMID: 38898440
Background: Respiratory Syncytial Virus (RSV) disease in young children ranges from mild cold symptoms to severe symptoms that require hospitalization and sometimes result in death. Studies have shown a statistical...
4.
Bhattacharya S, Myers J, Baker C, Guo M, Danopoulos S, Myers J, et al.
Genes (Basel)
. 2024 Mar;
15(3.
PMID: 38540357
While animal model studies have extensively defined the mechanisms controlling cell diversity in the developing mammalian lung, there exists a significant knowledge gap with regards to late-stage human lung development....
5.
Bandyopadhyay G, Jehrio M, Baker C, Bhattacharya S, Misra R, Huyck H, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Mar;
326(5):L604-L617.
PMID: 38442187
Postnatal lung development results in an increasingly functional organ prepared for gas exchange and pathogenic challenges. It is achieved through cellular differentiation and migration. Changes in the tissue architecture during...
6.
Chu C, Kim S, Pryhuber G, Mariani T, McGraw M
Am J Physiol Lung Cell Mol Physiol
. 2023 Dec;
326(2):L135-L148.
PMID: 38084407
Bronchiolitis obliterans (BO) is a fibrotic lung disease characterized by progressive luminal narrowing and obliteration of the small airways. In the nontransplant population, inhalation exposure to certain chemicals is associated...
7.
Moore B, Ballinger M, Bauer N, Blackwell T, Borok Z, Budinger G, et al.
Ann Am Thorac Soc
. 2023 Aug;
20(8):1077-1087.
PMID: 37526479
To identify barriers and opportunities for Ph.D., basic and translational scientists to be fully integrated into clinical units. In 2022, an committee of the American Thoracic Society developed a project...
8.
Dylag A, Misra R, Bandyopadhyay G, Poole C, Huyck H, Jehrio M, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Jul;
325(4):L419-L433.
PMID: 37489262
Bronchopulmonary dysplasia (BPD) is a disease of prematurity related to the arrest of normal lung development. The objective of this study was to better understand how proteome modulation and cell-type...
9.
Zhou T, Gilliam N, Li S, Spandau S, Osborn R, Connor S, et al.
mBio
. 2023 Apr;
14(3):e0025023.
PMID: 37074178
Defective viral genomes (DVGs) have been identified in many RNA viruses as a major factor influencing antiviral immune response and viral pathogenesis. However, the generation and function of DVGs in...
10.
Bhattacharya S, Cherry C, Deutsch G, Glass I, Mariani T, Al Alam D, et al.
bioRxiv
. 2023 Apr;
PMID: 37066313
Trisomy 21 (T21), resulting in Down Syndrome (DS), is the most prevalent chromosomal abnormality worldwide. While pulmonary disease is a major cause of morbidity and mortality in DS, the ontogeny...