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Jason R Myers

Explore the profile of Jason R Myers including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 1926
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Recent Articles
21.
Kurosaki T, Myers J, Maquat L
Methods . 2018 Dec; 155:68-76. PMID: 30576707
Nonsense-mediated mRNA decay (NMD) is a cellular mRNA degradation mechanism that inhibits the expression of aberrant mRNAs harboring premature termination codons (PTCs). Recent progress in transcriptome-wide sequencing techniques has revealed...
22.
Kurosaki T, Miyoshi K, Myers J, Maquat L
Nat Struct Mol Biol . 2018 Oct; 25(11):1059. PMID: 30353197
In the version of this paper originally published, in the PDF references 48-55 appeared in the reference list for the Methods section although they should have been in the reference...
23.
Kurosaki T, Miyoshi K, Myers J, Maquat L
Nat Struct Mol Biol . 2018 Oct; 25(10):940-950. PMID: 30275517
Nonsense-mediated messenger RNA decay (NMD) controls mRNA quality and degrades physiologic mRNAs to fine-tune gene expression in changing developmental or environmental milieus. NMD requires that its targets are removed from...
24.
Wang W, Friedland S, Guo B, ODell M, Alexander W, Whitney-Miller C, et al.
Gut . 2018 Sep; 68(7):1245-1258. PMID: 30228219
Objective: Here, we evaluate the contribution of AT-rich interaction domain-containing protein 1A (), the most frequently mutated member of the SWItch/sucrose non-fermentable (SWI/SNF) complex, in pancreatic homeostasis and pancreatic ductal...
25.
Kyle J, Clair G, Bandyopadhyay G, Misra R, Zink E, Bloodsworth K, et al.
Sci Rep . 2018 Sep; 8(1):13455. PMID: 30194354
Cell type-resolved proteome analyses of the brain, heart and liver have been reported, however a similar effort on the lipidome is currently lacking. Here we applied liquid chromatography-tandem mass spectrometry...
26.
Bandyopadhyay G, Huyck H, Misra R, Bhattacharya S, Wang Q, Mereness J, et al.
Am J Physiol Lung Cell Mol Physiol . 2018 Jul; 315(4):L576-L583. PMID: 29975103
Human lung morphogenesis begins by embryonic life and continues after birth into early childhood to form a complex organ with numerous morphologically and functionally distinct cell types. Pulmonary organogenesis involves...
27.
Pei S, Minhajuddin M, Adane B, Khan N, Stevens B, Mack S, et al.
Cell Stem Cell . 2018 Jun; 23(1):86-100.e6. PMID: 29910151
Leukemia stem cells (LSCs) are thought to drive the genesis of acute myeloid leukemia (AML) as well as relapse following chemotherapy. Because of their unique biology, developing effective methods to...
28.
Trembley M, Quijada P, Agullo-Pascual E, Tylock K, Colpan M, Dirkx Jr R, et al.
Circulation . 2018 May; 138(17):1864-1878. PMID: 29716942
Background: Hypertrophic cardiomyocyte growth and dysfunction accompany various forms of heart disease. The mechanisms responsible for transcriptional changes that affect cardiac physiology and the transition to heart failure are not...
29.
Cho H, Rambout X, Gleghorn M, Nguyen P, Phipps C, Miyoshi K, et al.
Genes Dev . 2018 Apr; 32(7-8):555-567. PMID: 29654059
Although peroxisome proliferator-activated receptor-γ (PPARγ) coactivator 1α (PGC-1α) is a well-established transcriptional coactivator for the metabolic adaptation of mammalian cells to diverse physiological stresses, the molecular mechanism by which it...
30.
Ram J, Flamm G, Balys M, Sivagnanalingam U, Rothberg P, Iqbal A, et al.
Blood Adv . 2018 Jan; 1(8):500-503. PMID: 29296967
The persistence of a mutation at the time of complete remission warrants germ line analysis.Not all patients harboring germ line mutations have a family history of AML.