Jason C Mixdorf
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Explore the profile of Jason C Mixdorf including associated specialties, affiliations and a list of published articles.
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18
Citations
53
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Recent Articles
11.
Luo N, Minne R, Gallant J, Gunaratne G, West J, Javeri S, et al.
Bioconjug Chem
. 2024 Mar;
35(3):389-399.
PMID: 38470611
The Mesenchymal Epithelial Transition (MET) receptor tyrosine kinase is upregulated or mutated in 5% of non-small-cell lung cancer (NSCLC) patients and overexpressed in multiple other cancers. We sought to develop...
12.
Koller A, Glaser O, DeLuca M, Motz R, Amason E, Carbo-Bague I, et al.
Angew Chem Int Ed Engl
. 2024 Mar;
63(18):e202319578.
PMID: 38442302
The development of inert, biocompatible chelation methods is required to harness the emerging positron emitting radionuclide Ti for radiopharmaceutical applications. Herein, we evaluate the Ti-coordination chemistry of four catechol-based, hexacoordinate...
13.
Lin W, Cabrera G, Aluicio-Sarduy E, Barnhart T, Mixdorf J, Li Z, et al.
Bioconjug Chem
. 2024 Feb;
35(3):412-418.
PMID: 38411531
Cobalt-sarcophagine complexes exhibit high kinetic inertness under various stringent conditions, but there is limited literature on radiolabeling and in vivo positron emission tomography (PET) imaging using no carrier added Co....
14.
Usman F, Gogoi A, Mixdorf J, Gutierrez O, Nguyen H
Angew Chem Int Ed Engl
. 2023 Oct;
62(48):e202314843.
PMID: 37856668
Although there are many methods for the asymmetric synthesis of monosubstituted allylic fluorides, construction of enantioenriched 1,2-disubstituted allylic fluorides has not been reported. To address this gap, we report an...
15.
Lin W, Aluicio-Sarduy E, Barrett K, Barnhart T, Mixdorf J, DeLuca M, et al.
Appl Radiat Isot
. 2023 Aug;
200:110980.
PMID: 37591186
Cobalt-55 and -58m form a theranostic pair that has relevant properties for cancer research. We report a cation exchange chromatography/extraction chromatography method that separates cyclotron-produced Co from Fe in <1.5 ...
16.
Koller A, Wang L, Deluca M, Glaser O, Robis M, Mixdorf J, et al.
Inorg Chem
. 2023 Jul;
62(50):20655-20665.
PMID: 37523384
The solution chemistry of the hydrolytic, early-transition-metal ions Ti and Sc represents a coordination chemistry challenge with important real-world implications, specifically in the context of Ti/Sc and Ti/Sc radiochemical separations....
17.
Mixdorf J, Hoffman S, Aluicio-Sarduy E, Barnhart T, Engle J, Ellison P
J Org Chem
. 2023 Feb;
88(4):2089-2094.
PMID: 36745853
A copper-mediated radiobromination of (hetero)aryl boronic pinacol esters is described. Cyclotron-produced [Br]bromide was isolated using an anion exchange cartridge, wherein the pre-equilibration and elution solutions played a critical role in...
18.
da Silva I, Johnson T, Mixdorf J, Aluicio-Sarduy E, Barnhart T, Nickles R, et al.
Molecules
. 2021 Dec;
26(24).
PMID: 34946596
Radionuclides emitting Auger electrons (AEs) with low (0.02-50 keV) energy, short (0.0007-40 µm) range, and high (1-10 keV/µm) linear energy transfer may have an important role in the targeted radionuclide...
19.
Mixdorf J, Murali D, Xin Y, DiFilippo A, Aluicio-Sarduy E, Barnhart T, et al.
Appl Radiat Isot
. 2021 Oct;
178:109954.
PMID: 34607293
[C]ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein, a biomarker for neuroinflammation. The goal of this work was to investigate alternative strategies for the radiochemical...
20.
Rodrigo S, Um C, Mixdorf J, Gunasekera D, Nguyen H, Luo L
Org Lett
. 2020 Jul;
22(17):6719-6723.
PMID: 32658484
Paired electrolysis has a limited reaction scope for organic synthesis because it is often not compatible with reactions involving short-lived intermediates. We addressed this limitation using alternating current electrolysis (ACE)....