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Paul A Ellison

Explore the profile of Paul A Ellison including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 501
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Recent Articles
1.
Tong J, Chen B, Volpi T, Li Y, Ellison P, Cai Z
J Labelled Comp Radiopharm . 2025 Feb; 68(1-2):e4135. PMID: 39995212
Poly (ADP-ribose) polymerase 1 (PARP1) plays critical roles in DNA repair, chromatin regulation, and cellular equilibrium, positioning it as a pivotal target for therapeutic interventions in cancer and central nervous...
2.
Lo Y, Miller A, Brown G, Peaslee G, Engle J, Ellison P
Appl Radiat Isot . 2025 Jan; 217():111654. PMID: 39754961
This work reports experimental Ge(d,n)As cross sections producing Arsenic-71 (t = 65.3 h, 28% β), a potentially useful diagnostic radionuclide. Target stacks containing two Ge foils, a Ni monitor foil,...
3.
Olson A, Verich F, Ellison P, Aluicio-Sarduy E, Nickles R, Mixdorf J, et al.
EJNMMI Radiopharm Chem . 2024 Oct; 9(1):72. PMID: 39438347
Background: Radiopharmaceutical therapy (RPT) uses radionuclides that decay via one of three therapeutically relevant decay modes (alpha, beta, and internal conversion (IC) / Auger electron (AE) emission) to deliver short...
4.
Kwon O, Hoffman S, Ellison P, Bednarz B
Cancers (Basel) . 2024 Jul; 16(13). PMID: 39001411
Radiopharmaceutical therapy (RPT) is evolving as a promising strategy for treating cancer. As interest grows in short-range particles, like Auger electrons, understanding the dose-response relationship at the deoxyribonucleic acid (DNA)...
5.
Kostelnik T, Olson A, Grundmane A, Ellison P, Mynerich J, Chen S, et al.
Nucl Med Biol . 2023 Jun; 122-123:108352. PMID: 37390607
Targeted Meitner-Auger Therapy (TMAT) has potential for personalized treatment thanks to its subcellular dosimetric selectivity, which is distinct from the dosimetry of β and α particle emission based Targeted Radionuclide...
6.
Becker K, Aluicio-Sarduy E, Bradshaw T, Hurley S, Olson A, Barrett K, et al.
Front Chem . 2023 May; 11:1167783. PMID: 37179772
Sc and Sc are both positron-emitting radioisotopes of scandium with suitable half-lives and favorable positron energies for clinical positron emission tomography (PET) imaging. Irradiation of isotopically enriched calcium targets has...
7.
Mixdorf J, Hoffman S, Aluicio-Sarduy E, Barnhart T, Engle J, Ellison P
J Org Chem . 2023 Feb; 88(4):2089-2094. PMID: 36745853
A copper-mediated radiobromination of (hetero)aryl boronic pinacol esters is described. Cyclotron-produced [Br]bromide was isolated using an anion exchange cartridge, wherein the pre-equilibration and elution solutions played a critical role in...
8.
Wei H, Jiang D, Yu B, Ni D, Li M, Long Y, et al.
Bioact Mater . 2022 May; 19:282-291. PMID: 35574055
Acute kidney injury (AKI) leads to unacceptably high mortality due to difficulties in timely intervention and less efficient renal delivery of therapeutic drugs. Here, a series of polyvinylpyrrolidone (PVP)-curcumin nanoparticles...
9.
da Silva I, Johnson T, Mixdorf J, Aluicio-Sarduy E, Barnhart T, Nickles R, et al.
Molecules . 2021 Dec; 26(24). PMID: 34946596
Radionuclides emitting Auger electrons (AEs) with low (0.02-50 keV) energy, short (0.0007-40 µm) range, and high (1-10 keV/µm) linear energy transfer may have an important role in the targeted radionuclide...
10.
Mixdorf J, Murali D, Xin Y, DiFilippo A, Aluicio-Sarduy E, Barnhart T, et al.
Appl Radiat Isot . 2021 Oct; 178:109954. PMID: 34607293
[C]ER176 is a next generation PET radioligand for imaging 18 kDa translocator protein, a biomarker for neuroinflammation. The goal of this work was to investigate alternative strategies for the radiochemical...