Jan Kisielow
Overview
Explore the profile of Jan Kisielow including associated specialties, affiliations and a list of published articles.
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28
Citations
1622
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Recent Articles
1.
Lu B, Lucca L, Lewis W, Wang J, Nogueira C, Heer S, et al.
Nat Immunol
. 2024 Nov;
26(1):82-91.
PMID: 39609626
Effective anti-tumor immunity is driven by cytotoxic CD8 T cells with specificity for tumor antigens. However, the factors that control successful tumor rejection are not well understood. Here we identify...
2.
Xu M, Ito-Kureha T, Kang H, Chernev A, Raj T, Hoefig K, et al.
Nat Commun
. 2024 Aug;
15(1):6632.
PMID: 39103338
No abstract available.
3.
Xu M, Ito-Kureha T, Kang H, Chernev A, Raj T, Hoefig K, et al.
Nat Commun
. 2024 Mar;
15(1):2194.
PMID: 38467629
The regulation of thymocyte development by RNA-binding proteins (RBPs) is largely unexplored. We identify 642 RBPs in the thymus and focus on Arpp21, which shows selective and dynamic expression in...
4.
Hafler D, Lu B, Lucca L, Lewis W, Wang J, Nogeuira C, et al.
Res Sq
. 2024 Mar;
PMID: 38464315
Effective anti-tumor immunity is largely driven by cytotoxic CD8 T cells that can specifically recognize tumor antigens. However, the factors which ultimately dictate successful tumor rejection remain poorly understood. Here...
5.
Tortola L, Piattini F, Hausmann A, Ampenberger F, Rosenwald E, Heer S, et al.
Mucosal Immunol
. 2022 May;
15(4):656-667.
PMID: 35589985
Nuclear factor-κB (NF-κB) is a transcription factor with a key role in a great variety of cellular processes from embryonic development to immunity, the outcome of which depends on the...
6.
Obermair F, Renoux F, Heer S, Lee C, Cereghetti N, Loi M, et al.
Sci Adv
. 2022 Apr;
8(17):eabl5394.
PMID: 35486722
Understanding peptide presentation by specific MHC alleles is fundamental for controlling physiological functions of T cells and harnessing them for therapeutic use. However, commonly used in silico predictions and mass...
7.
Diethelm P, Schmitz I, Iten I, Kisielow J, Matsushita M, Kopf M
Eur J Immunol
. 2022 Mar;
52(6):924-935.
PMID: 35344223
T-cell responses against tumors and pathogens are critically shaped by cosignaling molecules providing a second signal. Interaction of herpes virus entry mediator (HVEM, CD270, TNFRSF14) with multiple ligands has been...
8.
Haftmann C, Zwicky P, Ingelfinger F, Mair F, Floess S, Riedel R, et al.
Sci Immunol
. 2021 Nov;
6(65):eabf3111.
PMID: 34797691
Medullary thymic epithelial cells (mTECs) are key antigen-presenting cells mediating T cell tolerance to prevent harmful autoimmunity. mTECs both negatively select self-reactive T cells and promote the development of thymic...
9.
Hausmann A, Felmy B, Kunz L, Kroon S, Berthold D, Ganz G, et al.
J Exp Med
. 2021 Sep;
218(11).
PMID: 34529751
Intestinal epithelial cell (IEC) NF-κB signaling regulates the balance between mucosal homeostasis and inflammation. It is not fully understood which signals tune this balance and how bacterial exposure elicits the...
10.
Dunst J, Glaros V, Englmaier L, Sandoz P, Onfelt B, Kisielow J, et al.
J Leukoc Biol
. 2020 Jan;
107(6):1033-1044.
PMID: 31943366
Although γδTCRs were discovered more than 30 yr ago, principles of antigen recognition by these receptors remain unclear and the nature of these antigens is largely elusive. Numerous studies reported...