Annette Oxenius
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Explore the profile of Annette Oxenius including associated specialties, affiliations and a list of published articles.
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Articles
189
Citations
7695
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Recent Articles
1.
Barandun N, Meier B, Stehli G, Grabnitz F, Zangger N, Oxenius A
Cell Rep
. 2025 Jan;
44(1):115127.
PMID: 39764850
How a single, naive T cell can give rise to diverse progenies of effector and memory cells is not completely understood. One way to achieve this is by asymmetric cell...
2.
Yaniv Z, Anidi I, Arakkal L, Arroyo-Mejias A, Beuschel R, Borner K, et al.
ArXiv
. 2025 Jan;
PMID: 39764400
The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D and 3D immunofluorescence imaging methods. The design of the Knowledge-Base is modeled...
3.
Sparano C, Solis-Sayago D, Zangger N, Rindlisbacher L, Van Hove H, Vermeer M, et al.
J Exp Med
. 2024 Dec;
222(3).
PMID: 39692745
Group 1 innate lymphoid cells (ILCs) encompass NK cells and ILC1s, which have non-redundant roles in host protection against pathogens and cancer. Despite their circulating nature, NK cells can establish...
4.
Padhi C, Field C, Forneris C, Olszewski D, Fraley A, Sandu I, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2409026121.
PMID: 39585984
In contrast to the large body of work on bioactive natural products from individually cultivated bacteria, the chemistry of environmental microbial communities remains largely elusive. Here, we present a comprehensive...
5.
Bosch M, Kallin N, Donakonda S, Zhang J, Wintersteller H, Hegenbarth S, et al.
Nature
. 2024 Jul;
631(8022):867-875.
PMID: 38987588
Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide, in whom virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot eliminate HBV-infected hepatocytes. Here...
6.
Hale B, Severin Y, Graebnitz F, Stark D, Guignard D, Mena J, et al.
Science
. 2024 Jun;
384(6700):eadh8697.
PMID: 38843327
After antigen stimulation, naïve T cells display reproducible population-level responses, which arise from individual T cells pursuing specific differentiation trajectories. However, cell-intrinsic predeterminants controlling these single-cell decisions remain enigmatic. We...
7.
Elsayed A, Pluss L, Nideroest L, Rotta G, Thoma M, Zangger N, et al.
Mol Cancer Ther
. 2024 Apr;
23(7):1010-1020.
PMID: 38638035
Metastatic colorectal cancer remains a leading cause of cancer-related deaths, with a 5-year survival rate of only 15%. T cell-engaging bispecific antibodies (TCBs) represent a class of biopharmaceuticals that redirect...
8.
Cotet T, Agrafiotis A, Kreiner V, Kuhn R, Shlesinger D, Manero-Carranza M, et al.
Bioinformatics
. 2023 Sep;
39(9).
PMID: 37682115
Motivation: The maturation of systems immunology methodologies requires novel and transparent computational frameworks capable of integrating diverse data modalities in a reproducible manner. Results: Here, we present the ePlatypus computational...
9.
Pluss L, Peissert F, Elsayed A, Rotta G, Romer J, Dakhel Plaza S, et al.
MAbs
. 2023 May;
15(1):2217964.
PMID: 37243574
There are no effective treatment options for most patients with metastatic colorectal cancer (mCRC). mCRC remains a leading cause of tumor-related death, with a five-year survival rate of only 15%,...
10.
Grabnitz F, Stark D, Shlesinger D, Petkidis A, Borsa M, Yermanos A, et al.
Cell Rep
. 2023 May;
42(5):112468.
PMID: 37178119
The strength of T cell receptor (TCR) stimulation and asymmetric distribution of fate determinants are both implied to affect T cell differentiation. Here, we uncover asymmetric cell division (ACD) as...