Jan Kisielow
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Explore the profile of Jan Kisielow including associated specialties, affiliations and a list of published articles.
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28
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1622
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Recent Articles
11.
Cossarizza A, Chang H, Radbruch A, Acs A, Adam D, Adam-Klages S, et al.
Eur J Immunol
. 2019 Oct;
49(10):1457-1973.
PMID: 31633216
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry...
12.
Tan L, Sandrock I, Odak I, Aizenbud Y, Wilharm A, Barros-Martins J, et al.
Cell Rep
. 2019 Jun;
27(12):3657-3671.e4.
PMID: 31216482
IL-17-producing γδ T cells express oligoclonal Vγ4 and Vγ6 TCRs, mainly develop in the prenatal thymus, and later persist as long-lived self-renewing cells in all kinds of tissues. However, their...
13.
Piattini F, Le Foll C, Kisielow J, Rosenwald E, Nielsen P, Lutz T, et al.
Mol Metab
. 2019 May;
25:131-141.
PMID: 31076350
Objective: Leptin (Lep) plays a crucial role in controlling food intake and energy expenditure. Defective Lep/LepRb-signaling leads to fat accumulation, massive obesity, and the development of diabetes. We serendipitously noticed...
14.
Kisielow J, Obermair F, Kopf M
Nat Immunol
. 2019 Apr;
20(5):663.
PMID: 30944415
In the version of this article initially published, a reference (23) was cited incorrectly and two references were not included in the second sentence of the first paragraph of the...
15.
Kisielow J, Obermair F, Kopf M
Nat Immunol
. 2019 Mar;
20(5):652-662.
PMID: 30858620
αβ T cell antigen receptors (TCRs) bind complexes of peptide and major histocompatibility complex (pMHC) with low affinity, which poses a considerable challenge for the direct identification of αβ T...
16.
Spidale N, Sylvia K, Narayan K, Miu B, Frascoli M, Melichar H, et al.
Immunity
. 2018 Nov;
49(5):857-872.e5.
PMID: 30413363
Lineage-committed αβ and γδ T cells are thought to originate from common intrathymic multipotent progenitors following instructive T cell receptor (TCR) signals. A subset of lymph node and mucosal Vγ2...
17.
Muri J, Heer S, Matsushita M, Pohlmeier L, Tortola L, Fuhrer T, et al.
Nat Commun
. 2018 May;
9(1):1851.
PMID: 29749372
The thioredoxin-1 (Trx1) system is an important contributor to cellular redox balance and is a sensor of energy and glucose metabolism. Here we show critical c-Myc-dependent activation of the Trx1...
18.
Kisielow J, Kopf M
Curr Opin Immunol
. 2013 Apr;
25(2):181-8.
PMID: 23562386
Recent experiments indicate that in contrast to αβT cells, γδT cell effector functions are largely preprogrammed in the thymus during fetal life. However the thymus also exports juvenile γδT cells...
19.
Tortola L, Rosenwald E, Abel B, Blumberg H, Schafer M, Coyle A, et al.
J Clin Invest
. 2012 Oct;
122(11):3965-76.
PMID: 23064362
Psoriasis is a chronic inflammatory disorder of the skin affecting approximately 2% of the world's population. Accumulating evidence has revealed that the IL-23/IL-17/IL-22 pathway is key for development of skin...
20.
Kisielow J, Tortola L, Weber J, Karjalainen K, Kopf M
Blood
. 2011 Oct;
118(25):6591-600.
PMID: 22021367
In addition to adaptive T cells, the thymus supports the development of unconventional T cells such as natural killer T (NKT) and CD8αα intraepithelial lymphocytes (IELs), which have innate functional...