James Bagnall
Overview
Explore the profile of James Bagnall including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
531
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Preston R, Chrisp R, Dudek M, Morais M, Tian P, Williams E, et al.
Kidney Int
. 2024 Nov;
107(1):99-115.
PMID: 39515644
Kidney physiology shows diurnal variation, and a disrupted circadian rhythm is associated with kidney disease. However, it remains largely unknown whether glomeruli, the filtering units in the kidney, are under...
2.
Moran J, Feltham L, Bagnall J, Goldrick M, Lord E, Nettleton C, et al.
Front Immunol
. 2023 Sep;
14:1235675.
PMID: 37675103
Pathogens have developed intricate strategies to overcome the host's innate immune responses. In this paper we use live-cell microscopy with a single bacterium resolution to follow in real time interactions...
3.
Kalliara E, Kardynska M, Bagnall J, Spiller D, Muller W, Ruckerl D, et al.
Front Immunol
. 2022 Oct;
13:947213.
PMID: 36238296
Immune cells fine tune their responses to infection and inflammatory cues. Here, using live-cell confocal microscopy and mathematical modelling, we investigate interferon-induced JAK-STAT signalling in innate immune macrophages. We demonstrate...
4.
Manousaki A, Bagnall J, Spiller D, Balarezo-Cisneros L, White M, Delneri D
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955668
The quantification of low abundant membrane-binding proteins such as transcriptional factors and chaperones has proven difficult, even with the most sophisticated analytical technologies. Here, we exploit and optimise the non-invasive...
5.
Smyllie N, Bagnall J, Koch A, Niranjan D, Polidarova L, Chesham J, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(4).
PMID: 35046033
The ∼20,000 cells of the suprachiasmatic nucleus (SCN), the master circadian clock of the mammalian brain, coordinate subordinate cellular clocks across the organism, driving adaptive daily rhythms of physiology and...
6.
Bagnall J, Rowe W, Alachkar N, Roberts J, England H, Clark C, et al.
Cell Syst
. 2020 Sep;
11(3):300-314.e8.
PMID: 32918862
Single-cell gene expression is inherently variable, but how this variability is controlled in response to stimulation remains unclear. Here, we use single-cell RNA-seq and single-molecule mRNA counting (smFISH) to study...
7.
Paszek A, Kardynska M, Bagnall J, Smieja J, Spiller D, Widlak P, et al.
Cell Commun Signal
. 2020 May;
18(1):77.
PMID: 32448393
Background: Ability to adapt to temperature changes trough the Heat Shock Response (HSR) pathways is one of the most fundamental and clinically relevant cellular response systems. Heat Shock (HS) affects...
8.
Yang N, Smyllie N, Morris H, Goncalves C, Dudek M, Pathiranage D, et al.
PLoS Genet
. 2020 May;
16(4):e1008729.
PMID: 32352975
Evolutionarily conserved circadian clocks generate 24-hour rhythms in physiology and behaviour that adapt organisms to their daily and seasonal environments. In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus is...
9.
Kitchen G, Cunningham P, Poolman T, Iqbal M, Maidstone R, Baxter M, et al.
Proc Natl Acad Sci U S A
. 2020 Jan;
117(3):1543-1551.
PMID: 31900362
The circadian clock regulates many aspects of immunity. Bacterial infections are affected by time of day, but the mechanisms involved remain undefined. Here we show that loss of the core...
10.
Cunningham P, Meijer P, Nazgiewicz A, Anderson S, Borthwick L, Bagnall J, et al.
Proc Natl Acad Sci U S A
. 2019 Dec;
117(2):1139-1147.
PMID: 31879343
Pulmonary inflammatory responses lie under circadian control; however, the importance of circadian mechanisms in the underlying fibrotic phenotype is not understood. Here, we identify a striking change to these mechanisms...