Jake P Taylor-King
Overview
Explore the profile of Jake P Taylor-King including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
88
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0
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Recent Articles
1.
De Jonghe J, Opzoomer J, Vilas-Zornoza A, Nilges B, Crane P, Vicari M, et al.
Cell Genom
. 2024 Dec;
4(12):100723.
PMID: 39667347
Understanding the rapidly evolving landscape of single-cell and spatial omic technologies is crucial for advancing biomedical research and drug development. We provide a living review of both mature and emerging...
2.
De Jonghe J, Opzoomer J, Vilas-Zornoza A, Crane P, Nilges B, Vicari M, et al.
Nat Biotechnol
. 2024 Jul;
42(7):1017-1023.
PMID: 39020213
No abstract available.
3.
Peidli S, Green T, Shen C, Gross T, Min J, Garda S, et al.
Nat Methods
. 2024 Jan;
21(3):531-540.
PMID: 38279009
Analysis across a growing number of single-cell perturbation datasets is hampered by poor data interoperability. To facilitate development and benchmarking of computational methods, we collect a set of 44 publicly...
4.
Taylor-King J, Bronstein M, Roblin D
Clin Pharmacol Ther
. 2024 Jan;
115(4):655-657.
PMID: 38169071
No abstract available.
5.
Bertin P, Rector-Brooks J, Sharma D, Gaudelet T, Anighoro A, Gross T, et al.
Cell Rep Methods
. 2023 Oct;
3(10):100599.
PMID: 37797618
For large libraries of small molecules, exhaustive combinatorial chemical screens become infeasible to perform when considering a range of disease models, assay conditions, and dose ranges. Deep learning models have...
6.
In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis
Lara-Astiaso D, Goni-Salaverri A, Mendieta-Esteban J, Narayan N, Del Valle C, Gross T, et al.
Nat Genet
. 2023 Aug;
55(9):1542-1554.
PMID: 37580596
Cellular differentiation requires extensive alterations in chromatin structure and function, which is elicited by the coordinated action of chromatin and transcription factors. By contrast with transcription factors, the roles of...
7.
Taylor-King J
Trends Genet
. 2021 Oct;
38(4):317-320.
PMID: 34702579
Complex diseases, including ageing, often exhibit sexual dimorphism. These sex differences can obfuscate attribution to causal genes within a target ID campaign. Mendelian randomisation (MR)-inspired analysis provides a natural setting...
8.
Gaudelet T, Day B, Jamasb A, Soman J, Regep C, Liu G, et al.
Brief Bioinform
. 2021 May;
22(6).
PMID: 34013350
Graph machine learning (GML) is receiving growing interest within the pharmaceutical and biotechnology industries for its ability to model biomolecular structures, the functional relationships between them, and integrate multi-omic datasets...
9.
Taylor-King J, Buenzli P, Chapman S, Lynch C, Basanta D
Front Bioeng Biotechnol
. 2020 Aug;
8:757.
PMID: 32793566
Advanced cancers, such as prostate and breast cancers, commonly metastasize to bone. In the bone matrix, dendritic osteocytes form a spatial network allowing communication between osteocytes and the osteoblasts located...
10.
Taylor-King J, Riseth A, Macnair W, Claassen M
PLoS Comput Biol
. 2020 Jan;
16(1):e1007491.
PMID: 31923173
Recent high-dimensional single-cell technologies such as mass cytometry are enabling time series experiments to monitor the temporal evolution of cell state distributions and to identify dynamically important cell states, such...