Christoffer Mattsson Langseth
Overview
Explore the profile of Christoffer Mattsson Langseth including associated specialties, affiliations and a list of published articles.
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14
Citations
378
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Recent Articles
1.
De Jonghe J, Opzoomer J, Vilas-Zornoza A, Nilges B, Crane P, Vicari M, et al.
Cell Genom
. 2024 Dec;
4(12):100723.
PMID: 39667347
Understanding the rapidly evolving landscape of single-cell and spatial omic technologies is crucial for advancing biomedical research and drug development. We provide a living review of both mature and emerging...
2.
Lee H, Langseth C, Marco Salas S, Sariyar S, Metousis A, Rueda-Alana E, et al.
Development
. 2024 Aug;
151(16).
PMID: 39099456
Multiplexed spatial profiling of mRNAs has recently gained traction as a tool to explore the cellular diversity and the architecture of tissues. We propose a sensitive, open-source, simple and flexible...
3.
De Jonghe J, Opzoomer J, Vilas-Zornoza A, Crane P, Nilges B, Vicari M, et al.
Nat Biotechnol
. 2024 Jul;
42(7):1017-1023.
PMID: 39020213
No abstract available.
4.
Wernersson E, Gelali E, Girelli G, Wang S, Castillo D, Langseth C, et al.
Nat Methods
. 2024 Jun;
21(7):1245-1256.
PMID: 38844629
Microscopy-based spatially resolved omic methods are transforming the life sciences. However, these methods rely on high numerical aperture objectives and cannot resolve crowded molecular targets, limiting the amount of extractable...
5.
Zhang Y, Miller J, Park J, Lelieveldt B, Long B, Abdelaal T, et al.
Sci Rep
. 2023 Jun;
13(1):9567.
PMID: 37311768
With the advent of multiplex fluorescence in situ hybridization (FISH) and in situ RNA sequencing technologies, spatial transcriptomics analysis is advancing rapidly, providing spatial location and gene expression information about...
6.
Li X, Andrusivova Z, Czarnewski P, Langseth C, Andersson A, Liu Y, et al.
Nat Neurosci
. 2023 Apr;
26(5):891-901.
PMID: 37095395
The spatiotemporal regulation of cell fate specification in the human developing spinal cord remains largely unknown. In this study, by performing integrated analysis of single-cell and spatial multi-omics data, we...
7.
Hilscher M, Langseth C, Kukanja P, Yokota C, Nilsson M, Castelo-Branco G
BMC Biol
. 2022 May;
20(1):122.
PMID: 35610641
Background: Oligodendrocytes are glial cells that support and insulate axons in the central nervous system through the production of myelin. Oligodendrocytes arise throughout embryonic and early postnatal development from oligodendrocyte...
8.
van Bruggen D, Pohl F, Langseth C, Kukanja P, Lee H, Mossi Albiach A, et al.
Dev Cell
. 2022 May;
57(11):1421-1436.e5.
PMID: 35523173
Oligodendrogenesis in the human central nervous system has been observed mainly at the second trimester of gestation, a much later developmental stage compared to oligodendrogenesis in mice. Here, we characterize...
9.
Langseth C, Gyllborg D, Miller J, Close J, Long B, Lein E, et al.
Commun Biol
. 2021 Aug;
4(1):998.
PMID: 34429496
The ability to spatially resolve the cellular architecture of human cortical cell types over informative areas is essential to understanding brain function. We combined in situ sequencing gene expression data...
10.
Marco Salas S, Gyllborg D, Langseth C, Nilsson M
BMC Bioinformatics
. 2021 Aug;
22(1):391.
PMID: 34332548
Background: A range of spatially resolved transcriptomic methods has recently emerged as a way to spatially characterize the molecular and cellular diversity of a tissue. As a consequence, an increasing...