Jacob A VanderBurgh
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Explore the profile of Jacob A VanderBurgh including associated specialties, affiliations and a list of published articles.
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13
Citations
295
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Recent Articles
1.
VanderBurgh J, Corso G, Levy S, Craighead H
Biomed Microdevices
. 2024 Jan;
26(1):10.
PMID: 38194117
Cellular therapies have the potential to advance treatment for a broad array of diseases but rely on viruses for genetic reprogramming. The time and cost required to produce viruses has...
2.
VanderBurgh J, Corso G, Levy S, Craighead H
Res Sq
. 2023 Nov;
PMID: 37986928
Cellular therapies have the potential to advance treatment for a broad array of diseases but rely on viruses for genetic reprogramming. The time and cost required to produce viruses has...
3.
VanderBurgh J, Corso T, Levy S, Craighead H
Sci Rep
. 2023 May;
13(1):6857.
PMID: 37185305
Viral vectors represent a bottleneck in the manufacturing of cellular therapies. Electroporation has emerged as an approach for non-viral transfection of primary cells, but standard cuvette-based approaches suffer from low...
4.
Lopez-Cavestany M, Hahn S, Hope J, Reckhorn N, Greenlee J, Schwager S, et al.
iScience
. 2023 Mar;
26(4):106275.
PMID: 36950111
Cells utilize calcium channels as one of the main signaling mechanisms to sense changes in the extracellular space and convert these changes to intracellular signals. Calcium regulates several key signaling...
5.
VanderBurgh J, Potharazu A, Schwager S, Reinhart-King C
J Cell Sci
. 2020 Sep;
133(18).
PMID: 32878941
Intimal stiffening upregulates endothelial cell contractility, disrupting barrier integrity; however, intimal stiffening is non-uniform. The impact of local changes in intimal stiffness on proximal and distal cell-cell interactions is unknown....
6.
Zanotelli M, Rahman-Zaman A, VanderBurgh J, Taufalele P, Jain A, Erickson D, et al.
Nat Commun
. 2019 Dec;
10(1):5619.
PMID: 31797873
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Mosier J, Rahman-Zaman A, Zanotelli M, VanderBurgh J, Bordeleau F, Hoffman B, et al.
Biophys J
. 2019 Oct;
117(9):1692-1701.
PMID: 31623884
During metastasis, cancer cells navigate through a spatially heterogeneous extracellular matrix (ECM). Physical properties of ECM, including the degree of confinement, influence cell migration behavior. Here, utilizing in vitro three-dimensional...
8.
Zanotelli M, Rahman-Zaman A, VanderBurgh J, Taufalele P, Jain A, Erickson D, et al.
Nat Commun
. 2019 Sep;
10(1):4185.
PMID: 31519914
Cell migration during the invasion-metastasis cascade requires cancer cells to navigate a spatially complex microenvironment that presents directional choices to migrating cells. Here, we investigate cellular energetics during migration decision-making...
9.
Taufalele P, VanderBurgh J, Munoz A, Zanotelli M, Reinhart-King C
PLoS One
. 2019 May;
14(5):e0216537.
PMID: 31091287
Aligned collagen architecture is a characteristic feature of the tumor extracellular matrix (ECM) and has been shown to facilitate cancer metastasis using 3D in vitro models. Additional features of the...
10.
VanderBurgh J, Hotchkiss H, Potharazu A, Taufalele P, Reinhart-King C
Integr Biol (Camb)
. 2018 Nov;
10(12):734-746.
PMID: 30382278
Intimal stiffening has been linked with increased vascular permeability and leukocyte transmigration, hallmarks of atherosclerosis. However, recent evidence indicates age-related intimal stiffening is not uniform but rather characterized by increased...