Paul V Taufalele
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Explore the profile of Paul V Taufalele including associated specialties, affiliations and a list of published articles.
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17
Citations
417
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Recent Articles
1.
Taufalele P, Kirkham H, Reinhart-King C
Cell Mol Bioeng
. 2025 Feb;
18(1):29-38.
PMID: 39949487
Purpose: Altered tissue mechanics is a prominent feature of many pathological conditions including cancer. As such, much work has been dedicated to understanding how mechanical features of tissues contribute to...
2.
Zhang J, Mosier J, Wu Y, Waddle L, Taufalele P, Wang W, et al.
Adv Sci (Weinh)
. 2024 Aug;
11(32):e2400719.
PMID: 39189477
Collective cell migration is a model for nonequilibrium biological dynamics, which is important for morphogenesis, pattern formation, and cancer metastasis. The current understanding of cellular collective dynamics is based primarily...
3.
Schunk C, Wang W, Sabo L, Taufalele P, Reinhart-King C
Matrix Biol
. 2024 Aug;
133:77-85.
PMID: 39147247
To form blood vessels, endothelial cells rearrange their cytoskeleton, generate traction stresses, migrate, and proliferate, all of which require energy. Despite these energetic costs, stiffening of the extracellular matrix promotes...
4.
Wang W, Taufalele P, Millet M, Homsy K, Smart K, Berestesky E, et al.
Cell Rep
. 2023 Apr;
42(4):112338.
PMID: 37027295
During intravasation, cancer cells cross the endothelial barrier and enter the circulation. Extracellular matrix stiffening has been correlated with tumor metastatic potential; however, little is known about the effects of...
5.
Wang W, Hapach L, Griggs L, Smart K, Wu Y, Taufalele P, et al.
Sci Adv
. 2022 Nov;
8(46):eabo1673.
PMID: 36399580
Diabetes mellitus is a complex metabolic disorder that is associated with an increased risk of breast cancer. Despite this correlation, the interplay between tumor progression and diabetes, particularly with regard...
6.
Rowe M, Wang W, Taufalele P, Reinhart-King C
Soft Matter
. 2022 Nov;
18(44):8504-8513.
PMID: 36325938
Diabetes is associated with increased risk of breast cancer and worse prognoses for cancer patients. Hyperglycemia can result in increased glycation, the process wherein crosslinkages are formed between sugars and...
7.
Schwager S, Mosier J, Padmanabhan R, White A, Xing Q, Hapach L, et al.
iScience
. 2022 Oct;
25(10):105190.
PMID: 36274934
Intracellular and environmental cues result in heterogeneous cancer cell populations with different metabolic and migratory behaviors. Although glucose metabolism and epithelial-to-mesenchymal transition have previously been linked, we aim to understand...
8.
Taufalele P, Wang W, Simmons A, Southard-Smith A, Chen B, Greenlee J, et al.
Acta Biomater
. 2022 Apr;
163:365-377.
PMID: 35483629
The role of intratumor heterogeneity is becoming increasingly apparent in part due to expansion in single cell technologies. Clinically, tumor heterogeneity poses several obstacles to effective cancer therapy dealing with...
9.
Taufalele P, Reinhart-King C
Trends Cancer
. 2021 Aug;
7(10):883-885.
PMID: 34417163
Focus on metabolic reprogramming has re-emerged in recent years due to the far-reaching consequences of metabolism on nearly all cellular behaviors. In a recent study in Cell Metabolism, Tharp et...
10.
Hapach L, Carey S, Schwager S, Taufalele P, Wang W, Mosier J, et al.
Cancer Res
. 2021 May;
81(13):3649-3663.
PMID: 33975882
Although intratumoral genomic heterogeneity can impede cancer research and treatment, less is known about the effects of phenotypic heterogeneities. To investigate the role of cell migration heterogeneities in metastasis, we...