Harold G Craighead
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Explore the profile of Harold G Craighead including associated specialties, affiliations and a list of published articles.
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Articles
79
Citations
1747
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Recent Articles
1.
VanderBurgh J, Corso G, Levy S, Craighead H
Biomed Microdevices
. 2024 Jan;
26(1):10.
PMID: 38194117
Cellular therapies have the potential to advance treatment for a broad array of diseases but rely on viruses for genetic reprogramming. The time and cost required to produce viruses has...
2.
VanderBurgh J, Corso G, Levy S, Craighead H
Res Sq
. 2023 Nov;
PMID: 37986928
Cellular therapies have the potential to advance treatment for a broad array of diseases but rely on viruses for genetic reprogramming. The time and cost required to produce viruses has...
3.
VanderBurgh J, Corso T, Levy S, Craighead H
Sci Rep
. 2023 May;
13(1):6857.
PMID: 37185305
Viral vectors represent a bottleneck in the manufacturing of cellular therapies. Electroporation has emerged as an approach for non-viral transfection of primary cells, but standard cuvette-based approaches suffer from low...
4.
Noyce S, Vanfleet R, Craighead H, Davis R
Nanoscale Adv
. 2022 Sep;
1(3):1148-1154.
PMID: 36133213
Microscale porous carbon mechanical resonators were formed using carbon nanotube templated microfabrication. These cantilever resonators exhibited nanoscale porosity resulting in a high surface area to volume ratio which could enable...
5.
Single cell on-chip whole genome amplification via micropillar arrays for reduced amplification bias
Tian H, Benitez J, Craighead H
PLoS One
. 2018 Feb;
13(2):e0191520.
PMID: 29432426
Single cell whole genome amplification is susceptible to amplification biases that impact the accuracy of single cell sequencing data. To address this, we have developed a microfluidic device for the...
6.
Reinholt S, Craighead H
Anal Chem
. 2018 Jan;
90(4):2601-2608.
PMID: 29323871
We present a microfluidic device for specifically capturing cancer cells and isolating their genomic DNA (gDNA) for specific amplification and sequence analysis. To capture cancer cells within the device, nucleic...
7.
De Alba R, Abhilash T, Rand R, Craighead H, Parpia J
Nano Lett
. 2017 May;
17(7):3995-4002.
PMID: 28537401
We investigate the nonlinear mechanics of a bimetallic, optically absorbing SiN-Nb nanowire in the presence of incident laser light and a reflecting Si mirror. Situated in a standing wave of...
8.
Reinholt S, Ozer A, Lis J, Craighead H
Sci Rep
. 2016 Jul;
6:29771.
PMID: 27432610
We describe a multiplexed RNA aptamer selection to 19 different targets simultaneously using a microcolumn-based device, MEDUSA (Microplate-based Enrichment Device Used for the Selection of Aptamers), as well as a...
9.
Kelly C, Wakefield D, Holowka D, Craighead H, Baird B
ACS Nano
. 2014 Jul;
8(7):7392-404.
PMID: 25004429
The organization and dynamics of plasma membrane components at the nanometer scale are essential for biological functions such as transmembrane signaling and endocytosis. Planarized nanoscale apertures in a metallic film...
10.
Meng H, Pagano J, White B, Toyoda Y, Min I, Craighead H, et al.
PLoS One
. 2014 Mar;
9(3):e93052.
PMID: 24675636
SELEX, the process of selecting aptamers, is often hampered by the difficulty of preparing target molecules in their native forms and by a lack of a simple yet quantitative assay...