Stephen L Levy
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Explore the profile of Stephen L Levy including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
150
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0
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Recent Articles
1.
VanderBurgh J, Corso G, Levy S, Craighead H
Biomed Microdevices
. 2024 Jan;
26(1):10.
PMID: 38194117
Cellular therapies have the potential to advance treatment for a broad array of diseases but rely on viruses for genetic reprogramming. The time and cost required to produce viruses has...
2.
VanderBurgh J, Corso G, Levy S, Craighead H
Res Sq
. 2023 Nov;
PMID: 37986928
Cellular therapies have the potential to advance treatment for a broad array of diseases but rely on viruses for genetic reprogramming. The time and cost required to produce viruses has...
3.
VanderBurgh J, Corso T, Levy S, Craighead H
Sci Rep
. 2023 May;
13(1):6857.
PMID: 37185305
Viral vectors represent a bottleneck in the manufacturing of cellular therapies. Electroporation has emerged as an approach for non-viral transfection of primary cells, but standard cuvette-based approaches suffer from low...
4.
Benitez J, Topolancik J, Tian H, Wallin C, Latulippe D, Szeto K, et al.
Lab Chip
. 2012 Sep;
12(22):4848-54.
PMID: 23018789
We describe a microfluidic device for the extraction, purification and stretching of human chromosomal DNA from single cells. A two-dimensional array of micropillars in a microfluidic polydimethylsiloxane channel was designed...
5.
Cipriany B, Murphy P, Hagarman J, Cerf A, Latulippe D, Levy S, et al.
Proc Natl Acad Sci U S A
. 2012 May;
109(22):8477-82.
PMID: 22586076
Epigenetic modifications, such as DNA and histone methylation, are responsible for regulatory pathways that affect disease. Current epigenetic analyses use bisulfite conversion to identify DNA methylation and chromatin immunoprecipitation to...
6.
Cipriany B, Zhao R, Murphy P, Levy S, Tan C, Craighead H, et al.
Anal Chem
. 2010 Feb;
82(6):2480-7.
PMID: 20184350
Epigenetic states are governed by DNA methylation and a host of modifications to histones bound with DNA. These states are essential for proper developmentally regulated gene expression and are perturbed...
7.
Levy S, Craighead H
Chem Soc Rev
. 2010 Feb;
39(3):1133-52.
PMID: 20179829
Fluidic systems with nanometre length scales enable sensitive analysis of DNA molecules. Nanofluidic systems have been used to probe conformational, dynamic, and entropic properties of DNA molecules, to rapidly sort...
8.
Levy S, Mannion J, Cheng J, Reccius C, Craighead H
Nano Lett
. 2008 Oct;
8(11):3839-44.
PMID: 18844427
Single DNA molecules confined to nanoscale fluidic channels extend along the channel axis in order to minimize their conformational free energy. When such molecules are forced into a nanoscale fluidic...