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Imogen Moran

Explore the profile of Imogen Moran including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 543
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Recent Articles
1.
McDonald M, Khoo W, Ng P, Xiao Y, Zamerli J, Thatcher P, et al.
Cell . 2021 Apr; 184(7):1940. PMID: 33798441
No abstract available.
2.
McDonald M, Khoo W, Ng P, Xiao Y, Zamerli J, Thatcher P, et al.
Cell . 2021 Feb; 184(5):1330-1347.e13. PMID: 33636130
Osteoclasts are large multinucleated bone-resorbing cells formed by the fusion of monocyte/macrophage-derived precursors that are thought to undergo apoptosis once resorption is complete. Here, by intravital imaging, we reveal that...
3.
Moran I, Avery D, Payne K, Lenthall H, Davies E, Burns S, et al.
J Allergy Clin Immunol . 2019 Feb; 143(6):2302-2305. PMID: 30796983
No abstract available.
4.
Moran I, Grootveld A, Nguyen A, Phan T
Trends Immunol . 2018 Dec; 40(1):35-48. PMID: 30502023
Subcapsular sinus (SCS) macrophages are strategically positioned at the lymph-tissue interface in the lymph node to trap and present antigen to B cells. Recent murine data has shown that SCS...
5.
Moran I, Nguyen A, Khoo W, Butt D, Bourne K, Young C, et al.
Nat Commun . 2018 Aug; 9(1):3372. PMID: 30135429
Vaccine-induced immunity depends on the generation of memory B cells (MBC). However, where and how MBCs are reactivated to make neutralising antibodies remain unknown. Here we show that MBCs are...
6.
Nguyen A, Khoo W, Moran I, Croucher P, Phan T
Front Immunol . 2018 Jul; 9:1553. PMID: 30022984
Single-cell RNA sequencing (scRNA-Seq) is transforming our ability to characterize cells, particularly rare cells that are often overlooked in bulk population analytical approaches. This has lead to the discovery of...
7.
Warren S, Nobis M, Magenau A, Mohammed Y, Herrmann D, Moran I, et al.
Elife . 2018 Jul; 7. PMID: 29985127
Intravital microscopy can provide unique insights into the function of biological processes in a native context. However, physiological motion caused by peristalsis, respiration and the heartbeat can present a significant...
8.
Inoue T, Moran I, Shinnakasu R, Phan T, Kurosaki T
Immunol Rev . 2018 Apr; 283(1):138-149. PMID: 29664566
The successful establishment of humoral memory response depends on at least two layers of defense. Pre-existing protective antibodies secreted by long-lived plasma cells act as a first line of defense...
9.
Moran I, Phan T
Methods Mol Biol . 2017 Jun; 1623:59-72. PMID: 28589347
The germinal center (GC) reaction is the key process for the generation of high affinity antibodies to foreign antigen. Standard experimental techniques such as fluorescence-activated cell sorting and histology have...
10.
Suan D, Nguyen A, Moran I, Bourne K, Hermes J, Arshi M, et al.
Immunity . 2015 Apr; 42(4):704-18. PMID: 25840682
B helper follicular T (Tfh) cells are critical for long-term humoral immunity. However, it remains unclear how these cells are recruited and contribute to secondary immune responses. Here we show...