Stuart G Tangye
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Explore the profile of Stuart G Tangye including associated specialties, affiliations and a list of published articles.
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264
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17286
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Recent Articles
1.
Dale R, Mohammad S, Han V, Nishida H, Goel H, Tangye S, et al.
Dev Med Child Neurol
. 2025 Feb;
PMID: 39985218
We report eight children with de novo pathogenic DNA variants in chromatin-related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B. All children experienced infection or vaccine-provoked neuroregression or...
2.
Mackie J, Suan D, McNaughton P, Haerynck F, OSullivan M, Guerin A, et al.
Clin Exp Immunol
. 2025 Jan;
219(1).
PMID: 39836489
Introduction: Signal transducer and activator of transcription 3 (STAT3) orchestrates crucial immune responses through its pleiotropic functions as a transcription factor. Patients with germline monoallelic dominant negative or hypermorphic STAT3...
3.
Nieto-Patlan A, Ross J, Mohan S, Paczosa M, Soliman R, Sarmento O, et al.
J Allergy Clin Immunol
. 2025 Jan;
PMID: 39826876
Background: The Clinical Genome Resource (ClinGen) is an international collaborative effort among scientists and clinicians, diagnostic and research laboratories, and the patient community. Using a standardized framework, ClinGen has established...
4.
Rao G, Mack C, Nguyen T, Wong N, Payne K, Worley L, et al.
J Allergy Clin Immunol
. 2024 Dec;
PMID: 39622295
Background: CD4 T cells play essential roles in adaptive immunity. Distinct CD4 T-cell subsets-T1, T2, T17, T22, T follicular helper, and regulatory T cells-have been identified, and their contributions to...
5.
Shrestha L, Tungatt K, Aggarwal A, Stubis A, Fewings N, Fichter C, et al.
EBioMedicine
. 2024 Nov;
110:105461.
PMID: 39612651
Background: Current literature informs us that bivalent vaccines will generate a broader serum neutralizing antibody response to multiple SARS-CoV-2 variants, but studies on how this breadth relates to the memory...
6.
Ogishi M, Kitaoka K, Good-Jacobson K, Rinchai D, Zhang B, Wang J, et al.
Immunity
. 2024 Nov;
57(12):2790-2807.e15.
PMID: 39603236
T follicular helper (Tfh) cells abundantly express the immunoreceptor programmed cell death protein 1 (PD-1), and the impact of PD-1 deficiency on antibody (Ab)-mediated immunity in mice is associated with...
7.
Gervais A, Bastard P, Bizien L, Delifer C, Tiberghien P, Rodrigo C, et al.
J Exp Med
. 2024 Nov;
221(12.
PMID: 39485284
Arboviral diseases are a growing global health concern. Pre-existing autoantibodies (auto-Abs) neutralizing type I interferons (IFNs) can underlie encephalitis due to West Nile virus (WNV) (∼40% of patients) and tick-borne...
8.
Bohlen J, Bagaric I, Vatovec T, Ogishi M, Ahmed S, Cederholm A, et al.
J Clin Invest
. 2024 Oct;
134(20).
PMID: 39403923
Patients heterozygous for germline CBL loss-of-function (LOF) variants can develop myeloid malignancy, autoinflammation, or both, if some or all of their leukocytes become homozygous for these variants through somatic loss...
9.
Arango-Franco C, Ogishi M, Unger S, Delmonte O, Orrego J, Yatim A, et al.
J Clin Invest
. 2024 Oct;
134(19).
PMID: 39352394
Infants with biallelic IL7R loss-of-function variants have severe combined immune deficiency (SCID) characterized by the absence of autologous T lymphocytes, but normal counts of circulating B and NK cells (T-B+NK+...
10.
Huynh A, Gray P, Sullivan A, Mackie J, Guerin A, Rao G, et al.
J Clin Immunol
. 2024 Sep;
45(1):11.
PMID: 39297999
No abstract available.