Ilona Krol
Overview
Explore the profile of Ilona Krol including associated specialties, affiliations and a list of published articles.
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17
Citations
1838
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Recent Articles
1.
Kurzeder C, Nguyen-Strauli B, Krol I, Ring A, Castro-Giner F, Nuesch M, et al.
Nat Med
. 2025 Jan;
PMID: 39856336
The presence of circulating tumor cell (CTC) clusters is associated with disease progression and reduced survival in a variety of cancer types. In breast cancer, preclinical studies showed that inhibitors...
2.
Schwab F, Scheidmann M, Ozimski L, Kling A, Armbrecht L, Ryser T, et al.
Microsyst Nanoeng
. 2022 Dec;
8:130.
PMID: 36561926
Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment. Current clinical practice for treatment decision-making is commonly based on...
3.
Diamantopoulou Z, Castro-Giner F, Schwab F, Foerster C, Saini M, Budinjas S, et al.
Nature
. 2022 Jun;
607(7917):156-162.
PMID: 35732738
The metastatic spread of cancer is achieved by the haematogenous dissemination of circulating tumour cells (CTCs). Generally, however, the temporal dynamics that dictate the generation of metastasis-competent CTCs are largely...
4.
Scheidmann M, Castro-Giner F, Strittmatter K, Krol I, Paasinen-Sohns A, Scherrer R, et al.
Cancer Res
. 2021 Dec;
82(4):681-694.
PMID: 34916221
Significance: A loss-of-function CRISPR screen in human CTC-derived xenografts identifies genes critical for individual steps of the metastatic cascade, suggesting novel drivers and treatment opportunities for metastatic breast cancers.
5.
Belthier G, Homayed Z, Grillet F, Duperray C, Vendrell J, Krol I, et al.
Cancers (Basel)
. 2021 Oct;
13(19).
PMID: 34638450
Circulating tumor cells (CTCs) are promising diagnostic and prognostic tools for clinical use. In several cancers, including colorectal and breast, the CTC load has been associated with a therapeutic response...
6.
Krol I, Schwab F, Carbone R, Ritter M, Picocci S, De Marni M, et al.
Br J Cancer
. 2021 Mar;
125(1):23-27.
PMID: 33762721
Circulating tumour cell (CTC) clusters have been proposed to be major players in the metastatic spread of breast cancer, particularly during advanced disease stages. Yet, it is unclear whether or...
7.
Weth A, Krol I, Priesner K, Donato C, Pirker S, Wolf C, et al.
Sci Rep
. 2020 Jun;
10(1):10181.
PMID: 32576883
Circulating tumor cells (CTCs) are derivatives of solid cancerous lesions that detach from the tumor mass and enter the blood circulation. CTCs are considered to be the precursors of metastasis...
8.
Padmanaban V, Krol I, Suhail Y, Szczerba B, Aceto N, Bader J, et al.
Nature
. 2019 Sep;
573(7774):439-444.
PMID: 31485072
Metastasis is the major driver of death in patients with cancer. Invasion of surrounding tissues and metastasis have been proposed to initiate following loss of the intercellular adhesion protein, E-cadherin,...
9.
Szczerba B, Castro-Giner F, Vetter M, Krol I, Gkountela S, Landin J, et al.
Nature
. 2019 Feb;
566(7745):553-557.
PMID: 30728496
A better understanding of the features that define the interaction between cancer cells and immune cells is important for the development of new cancer therapies. However, focus is often given...
10.
Gkountela S, Castro-Giner F, Szczerba B, Vetter M, Landin J, Scherrer R, et al.
Cell
. 2019 Jan;
176(1-2):98-112.e14.
PMID: 30633912
The ability of circulating tumor cells (CTCs) to form clusters has been linked to increased metastatic potential. Yet biological features and vulnerabilities of CTC clusters remain largely unknown. Here, we...