Viola Heinzelmann-Schwarz
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Explore the profile of Viola Heinzelmann-Schwarz including associated specialties, affiliations and a list of published articles.
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93
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2565
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Recent Articles
1.
Chinczewski L, Harter P, Heukamp L, Mayr D, Grimm C, Heinzelmann-Schwarz V, et al.
Arch Gynecol Obstet
. 2025 Mar;
PMID: 40069521
Introduction: Homologous recombination deficiency (HRD) is a key biomarker in the management of high-grade serous ovarian cancer (HGSOC), guiding treatment decisions, particularly regarding the use of poly(ADP-ribose) polymerase inhibitors (PARPi)....
2.
Vergote I, Copeland L, Van Gorp T, Laenen A, Scambia G, Thaker P, et al.
Eur J Cancer
. 2025 Feb;
219:115306.
PMID: 40010134
Purpose: Tumor Treating Fields (TTFields) are electric fields that disrupt processes critical for cancer cell viability and tumor progression. The pivotal, phase 3 ENGOT-ov50/GOG-3029/INNOVATE-3 study evaluated efficacy and safety of...
3.
Kurzeder C, Nguyen-Strauli B, Krol I, Ring A, Castro-Giner F, Nuesch M, et al.
Nat Med
. 2025 Jan;
PMID: 39856336
The presence of circulating tumor cell (CTC) clusters is associated with disease progression and reduced survival in a variety of cancer types. In breast cancer, preclinical studies showed that inhibitors...
4.
Tundo S, Trefny M, Rodic A, Grueninger O, Brodmann N, Borsch A, et al.
J Immunother Cancer
. 2024 Nov;
12(11).
PMID: 39551607
Background: T cell-based immunotherapies including immune checkpoint blockade and chimeric antigen receptor T cells can induce durable responses in patients with cancer. However, clinical efficacy is limited due to the...
5.
Wegmann R, Bonilla X, Casanova R, Chevrier S, Coelho R, Esposito C, et al.
Nat Commun
. 2024 Oct;
15(1):9402.
PMID: 39477946
Deep single-cell multi-omic profiling offers a promising approach to understand and overcome drug resistance in relapsed or refractory (rr) acute myeloid leukemia (AML). Here, we combine single-cell ex vivo drug...
6.
Speck N, Stoffel J, Wendelspiess S, Appenzeller-Herzog C, Schaefer K, Kouba L, et al.
Curr Oncol
. 2024 Oct;
31(10):6300-6313.
PMID: 39451774
Background: Patient-reported outcome measures (PROMs) have gained increased importance in assessing outcomes after reconstructive surgery. This also applies to the reconstruction of vulvoperineal defects after resection of gynecological or colorectal...
7.
Zwimpfer T, Ewald H, Bilir E, Jayawardana M, Appenzeller-Herzog C, Bizzarri N, et al.
Cochrane Database Syst Rev
. 2024 Sep;
9:CD015896.
PMID: 39312297
This is a protocol for a Cochrane Review (prognosis). The objectives are as follows: To evaluate the predictive value of the prognostic factor HRD status, as determined by various clinically...
8.
Labrosse K, Lombardo F, Rimmer N, Nunez Lopez M, Fedier A, Heinzelmann-Schwarz V, et al.
STAR Protoc
. 2024 Aug;
5(3):103274.
PMID: 39172645
Three-dimensional (3D) ex vivo cultures allow the study of cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring on-target drug sensitivity in a scaffold-free 3D culture...
9.
Cumin C, Gee L, Litfin T, Muchabaiwa R, Martin G, Cooper O, et al.
Anal Chem
. 2024 Jul;
96(28):11163-11171.
PMID: 38953530
Glycans on proteins and lipids play important roles in maturation and cellular interactions, contributing to a variety of biological processes. Aberrant glycosylation has been associated with various human diseases including...
10.
Wendelspiess S, Kouba L, Stoffel J, Speck N, Appenzeller-Herzog C, Gahl B, et al.
Cancers (Basel)
. 2024 Jun;
16(12).
PMID: 38927919
Background: Patients with advanced vulvoperineal cancer require a multidisciplinary treatment approach to ensure oncological safety, timely recovery, and the highest possible quality of life (QoL). Reconstructions in this region often...