Ilia D Vainchtein
Overview
Explore the profile of Ilia D Vainchtein including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
1413
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Barron J, Mroz N, Taloma S, Dahlgren M, Ortiz-Carpena J, Keefe M, et al.
Science
. 2024 Oct;
386(6721):eadi1025.
PMID: 39480923
The innate immune system shapes brain development and is implicated in neurodevelopmental diseases. It is critical to define the relevant immune cells and signals and their impact on brain circuits....
2.
Escoubas C, Dorman L, Nguyen P, Lagares-Linares C, Nakajo H, Anderson S, et al.
Cell
. 2024 Mar;
187(8):1936-1954.e24.
PMID: 38490196
Microglia are brain-resident macrophages that shape neural circuit development and are implicated in neurodevelopmental diseases. Multiple microglial transcriptional states have been defined, but their functional significance is unclear. Here, we...
3.
Barron J, Mroz N, Taloma S, Dahlgren M, Ortiz-Carpena J, Dorman L, et al.
bioRxiv
. 2023 Mar;
PMID: 36993292
The innate immune system plays essential roles in brain synaptic development, and immune dysregulation is implicated in neurodevelopmental diseases. Here we show that a subset of innate lymphocytes (group 2...
4.
Han R, Vainchtein I, Schlachetzki J, Cho F, Dorman L, Ahn E, et al.
J Exp Med
. 2022 Dec;
220(2).
PMID: 36520518
Microglia are critical regulators of brain development that engulf synaptic proteins during postnatal synapse remodeling. However, the mechanisms through which microglia sense the brain environment are not well defined. Here,...
5.
Vainchtein I, Alsema A, Dubbelaar M, Grit C, Vinet J, van Weering H, et al.
Glia
. 2022 Nov;
71(3):588-601.
PMID: 36377669
Multiple sclerosis (MS) is the most common inflammatory, demyelinating and neurodegenerative disease of the central nervous system in young adults. Chronic-relapsing experimental autoimmune encephalomyelitis (crEAE) in Biozzi ABH mice is...
6.
Cho F, Vainchtein I, Voskobiynyk Y, Morningstar A, Aparicio F, Higashikubo B, et al.
Sci Transl Med
. 2022 Jul;
14(652):eabj4310.
PMID: 35857628
Inflammatory processes induced by brain injury are important for recovery; however, when uncontrolled, inflammation can be deleterious, likely explaining why most anti-inflammatory treatments have failed to improve neurological outcomes after...
7.
Escoubas C, Dorman L, Nguyen P, Lagares-Linares C, Nakajo H, Anderson S, et al.
bioRxiv
. 2022 Mar;
PMID: 35233577
Microglia are brain resident phagocytes that can engulf synaptic components and extracellular matrix as well as whole neurons. However, whether there are unique molecular mechanisms that regulate these distinct phagocytic...
8.
Kuhn J, Vainchtein I, Braz J, Hamel K, Bernstein M, Craik V, et al.
Elife
. 2021 Oct;
10.
PMID: 34652270
Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition characterized by mechanical hypersensitivity. We previously identified microglial activation via release of colony-stimulating factor 1 (CSF1) from injured sensory...
9.
Silva N, Dorman L, Vainchtein I, Horneck N, Molofsky A
Nat Commun
. 2021 Oct;
12(1):5916.
PMID: 34625548
Microglia are brain resident macrophages that play vital roles in central nervous system (CNS) development, homeostasis, and pathology. Microglia both remodel synapses and engulf apoptotic cell corpses during development, but...
10.
Gergues M, Han K, Choi H, Brown B, Clausing K, Turner V, et al.
Nat Neurosci
. 2021 Sep;
24(11):1637.
PMID: 34552273
No abstract available.