Ian W Dawes
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Explore the profile of Ian W Dawes including associated specialties, affiliations and a list of published articles.
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79
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2388
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Recent Articles
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2.
Ayer A, Fazakerley D, Suarna C, Maghzal G, Sheipouri D, Lee K, et al.
Redox Biol
. 2021 Sep;
46:102127.
PMID: 34521065
Mitochondrial energy production and function rely on optimal concentrations of the essential redox-active lipid, coenzyme Q (CoQ). CoQ deficiency results in mitochondrial dysfunction associated with increased mitochondrial oxidative stress and...
3.
Dawes I, Perrone G
FEMS Yeast Res
. 2019 Dec;
20(1).
PMID: 31816015
There has long been speculation about the role of various stresses in ageing. Some stresses have beneficial effects on ageing-dependent on duration and severity of the stress, others have negative...
4.
Dawes I
FEMS Yeast Res
. 2016 May;
16(4).
PMID: 27189365
Retrospective articles are an excuse for a rosy tinted view of one's life. This fully expurgated version is no exception. No "what the butler saw" or the vilification of enemies...
5.
Qi Y, Kapterian T, Du X, Ma Q, Fei W, Zhang Y, et al.
J Lipid Res
. 2016 Mar;
57(5):767-80.
PMID: 26946540
The expansion of lipid droplets (LDs) and the differentiation of preadipocytes are two important aspects of mammalian lipid storage. In this study, we examined the role of CDP-diacylglycerol (DAG) synthases...
6.
Andrisic L, Collinson E, Tehlivets O, Perak E, Zarkovic T, Dawes I, et al.
Mol Cell Biochem
. 2014 Oct;
399(1-2):27-37.
PMID: 25280400
Pathophysiology of polyunsaturated fatty acids (PUFAs) is associated with aberrant lipid and oxygen metabolism. In particular, under oxidative stress, PUFAs are prone to autocatalytic degradation via peroxidation, leading to formation...
7.
Ayer A, Gourlay C, Dawes I
FEMS Yeast Res
. 2013 Oct;
14(1):60-72.
PMID: 24164795
Ageing cells undergo changes in redox homeostasis and acquire high levels of reactive oxygen species (ROS). Because accumulation of ROS involves a change in redox state of cells, functions that...
8.
Smethurst D, Dawes I, Gourlay C
FEMS Yeast Res
. 2013 Oct;
14(1):89-95.
PMID: 24151902
The decision to proliferate, to activate stress response mechanisms or to initiate cell death lies at the heart of the maintenance of a healthy cell population. Within multicellular and colony-forming...
9.
Jarolim S, Ayer A, Pillay B, Gee A, Phrakaysone A, Perrone G, et al.
G3 (Bethesda)
. 2013 Oct;
3(12):2321-33.
PMID: 24142923
The heat-shock response in cells, involving increased transcription of a specific set of genes in response to a sudden increase in temperature, is a highly conserved biological response occurring in...
10.
Aung-Htut M, Lam Y, Lim Y, Rinnerthaler M, Gelling C, Yang H, et al.
Oxid Med Cell Longev
. 2013 Aug;
2013:636287.
PMID: 23936612
In Saccharomyces cerevisiae, mitochondrial morphology changes when cells are shifted between nonfermentative and fermentative carbon sources. Here, we show that cells of S. cerevisiae grown in different glucose concentrations display...